To scale up screens with a readout like Cell Painting or RNA-seq, people are starting to just stack up multiple perturbations on top of each other. (3/n)
Comments
Log in with your Bluesky account to leave a comment
One set of assumptions leads to a really cute optimality result. If you screen N perturbations and expect K of them to each individually be lethal, then allocate each treatment to 1 out of every K+2 samples.
I thought that was nice. Hope you enjoyed it too.
(n/n)
Comments
https://ekernf01.github.io/multiplexed_perturbation_studies/ (5/n)
I thought that was nice. Hope you enjoyed it too.
(n/n)