The brain drain will be when scientists are forced into other careers/jobs so that they can keep paying the bills. They will never return.

There aren't enough science jobs in other countries to absorb even a fraction of those laid off.
Reposted from Edward Nirenberg
On a basic level- you can't expect US talent to sit on their hands and wait until maybe, hopefully there's a job for them. A handful might be able to do that, but the majority are going to leave. Countries are actively seeking to take advantage of US brain drain.

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