But when increased immunogenicity was observed in cancer cells in response to blocking a same oncoprotein, it was explained by elegant specific molecular mechanisms merely in the context of anti-tumor immunity without considering reduced tumorigenicity. 🧐
Reposted from
Ying Cao
Inhibition of an oncoprotein in cancer cells leads to smaller tumor formation in both immunodeficient&syngeneic mice, meaning reduced tumorigenicity&increased immunogenicity. How are they connected?
See Preprint.👇
www.biorxiv.org/content/10.1...
See Preprint.👇
www.biorxiv.org/content/10.1...
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