Numerous studies showed that inhibition of an endogenous oncoprotein, Kras, c-myc, bcat, ezh2... causes decrease in tumorigenicity but also increase in antitumor immunity.
(In fact, a typical oncoprotein regulates almost all traits of cancer cells)
@cp-cancercell.bsky.social
(In fact, a typical oncoprotein regulates almost all traits of cancer cells)
@cp-cancercell.bsky.social
Reposted from
Ying Cao
Any treatment causes increase in anti-tumor immune response.
@cp-cancercell.bsky.social
General rule of cancer cell tumorigenicity and immunogenicity.
“Tumorigenicity and immunogenicity are inversely correlated and determined by differentiation status of cancer cells“ biorxiv.org/content/10.1...
@cp-cancercell.bsky.social
General rule of cancer cell tumorigenicity and immunogenicity.
“Tumorigenicity and immunogenicity are inversely correlated and determined by differentiation status of cancer cells“ biorxiv.org/content/10.1...
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