New PLRC-funded work out from Rob Wust & team! Skeletal muscles in #LongCovid and ME *differ* from skeletal muscles induced by bedrest. LC and ME is not deconditioning! 1/ www.medrxiv.org/content/10.1... - ThreadSky

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patientled.bsky.social • 29 days ago

New PLRC-funded work out from Rob Wust & team!

Skeletal muscles in #LongCovid and ME *differ* from skeletal muscles induced by bedrest.

LC and ME is not deconditioning! 1/
https://www.medrxiv.org/content/10.1101/2025.05.02.25326885v1

Comments

patientled.bsky.social•29 days ago

Bedrest caused muscle atrophy, & the reduced oxidative phosphorylation related to reductions in maximal oxygen uptake.

Patients with #LongCovid & ME/CFS didn't have muscle atrophy, but had less capillaries & more glycolytic fibers, none associated with maximal oxygen uptake. 2/

patientled.bsky.social•29 days ago

This research was part of our Patient-Led Research Fund (PLRF) funded by Balvi! You can see other projects👇 3/
https://patientresearchcovid19.com/projects/patient-led-research-fund/

cffnthmrnng.bsky.social•29 days ago

📌

patientled.bsky.social•29 days ago

Thank you to Rob Wust and team for continued incredible work!! This is the kind of research that moves the field 💓 4/

jeshyr.bsky.social•29 days ago

This is awesome! What would be the implications for the types of rehab needed for patients coming out of prolonged bedrest (many years) due to ME/CFS starting to go into remission?

oevie.bsky.social•28 days ago

📌

breakliquid.bsky.social•29 days ago

That’s a lot of acronyms

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