The meticulous development with our collaborators from SCIEX (@stevetate_absx and the magnificent team) was worth the effort, seeing gains between 30-40% in Protein IDs and improved quantitative performance in high-throughput, as well as with low-input proteomics applications.
We are super thrilled to see ZT Scan DIA leading to insight from miniscule proteome samples, in clinical proteomics and functional proteomics studies that depend on highly precise protein quantification from large sample series.
Beyond support by SCIEX, we acknowledge funding from the BMBF, MSCoreSys, the SFB TRR186 and @erc.europa.eu.
A special Thanks to everyone involved from the Ralser Lab (https://ralser.group/), SCIEX @sciex.bsky.social, as well as @vadim-demichev.bsky.social and @christophmessner.bsky.social.
What does dwell time mean in the method? 6.7ms implies 10 trap shots (0.67ms each at 1500 Hz), but out of sync to the 641 Hz spectral acquisition (1.56ms).
Is each spectrum then an average of 2 shots, plus some other overhead on top?
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A special Thanks to everyone involved from the Ralser Lab (https://ralser.group/), SCIEX @sciex.bsky.social, as well as @vadim-demichev.bsky.social and @christophmessner.bsky.social.
Is each spectrum then an average of 2 shots, plus some other overhead on top?