Delighted to share this paper out via Virus Evolution:
https://academic.oup.com/ve/advance-article/doi/10.1093/ve/veae104/7912585
in which we develop and assess a quantitative method to infer phage and bacterial mutations driving changes in infection phenotypes arising in coevolutionary dynamics.
a 🧵 about people (and some science)
https://academic.oup.com/ve/advance-article/doi/10.1093/ve/veae104/7912585
in which we develop and assess a quantitative method to infer phage and bacterial mutations driving changes in infection phenotypes arising in coevolutionary dynamics.
a 🧵 about people (and some science)
Comments
Identifying mutational determinants of phage-bacteria infection remains a foundational challenge in ecological/therapeutic contexts. This type of inference is challenging at the strain-level, given uncharacterized defense and counter-defense mutations.