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adhasarathy.bsky.social
Chromatin, TFs, epigenetic memory, and Epithelial- mesenchymal cell state transitions. Also will post about dogs/ cats/ animals/ nature.
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If heterochromatin is really a liquid-like condensate, why is it not spherical? We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments www.biorxiv.org/content/10.1...

Join us next Wed, for three amazing ECR researchers_ @fueyoraquel.bsky.social, @kaiamattioli.bsky.social and Laura talk about their work in #FragileNucleosome seminar series! In case you haven't joined any of the previous 2025 sessions, here is registration link: us06web.zoom.us/webinar/regi...

"Every gun that is made, every warship launched, every rocket fired signifies, in the final sense, a theft from those who hunger and are not fed, those who are cold and are not clothed."  -Dwight D. Eisenhower, 1953

🚀🚀 I'm starting my own lab @ HKU ! ! The lab will be investigating how cells build complex tissues — with a focus on tissue boundaries, niche establishment, and many open questions sparked by our recent work on trunk-organoids rdcu.be/eqsho 🫡🫡

“.. Jesus, that ear. He should donate it to the Smithsonian. .. He made all his records with four tracks, but you couldn't make his records if you had a hundred tracks today.” - Bob Dylan, on Brian Wilson #RIP “Good Vibrations” (1966)

Our dog is vey interested in this fledgling crow on our lawn. It can’t fly yet and the parents are still feeding it.

Donate to the Summer Fight For Science now. actionnetwork.org/fundraising/...

Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪 www.richmondscientific.com/how-a-discov...

Ahead of No Kings Day, a couple trainings we have coming up that might be useful: Safety and Deescalation: www.mobilize.us/nokings/even... Know Your Rights (w/ACLU): act.aclu.org/a/2025-kyr-t...

The astounding contribution of US academic science to new medicines www.statnews.com/2025/06/06/u...

NEW: Important Context spoke with a dozen people working at NIH about Director Jay Bhattacharya. The descriptions were universally unflattering, painting the health economist as ineffectual, dishonest, ideological, arrogant, and uncommitted to science. www.importantcontext.news/p/out-of-his...

Just published, expansion in situ genome sequencing, where you can sequence DNA while still inside the cell, mapping its organization relative to proteins and other markers, with the help of expansion microscopy! Led by @jbuenrostro.bksy.social. www.science.org/doi/10.1126/...

Everyone should watch and share. Thank you David. youtu.be/8YhJM6zxYDw

Heads up all

One problem we face today is how few people understand the science that helps us all. Some scientists are able to explain the importance of their work. @baym.lol of Harvard University is one of them. Science is for everyone, and benefits us all more than most people know.

Let's talk about these two department store owners: brother and sister Louis Bamberger and Caroline Bamberger Fuld. From Newark, New Jersey. They are random people, basically. But in the late 1920s, with fascism taking over Europe, they made a choice that profoundly changed the world: 🧵

🧪Did you know that America is known for its cancer research b/c of the National Cancer Act in 1971 signed by Nixon. Mary Lasker took her cause to congress and the American public as a leading proponent of the National Cancer Act. She said, "If you think research is expensive, try disease!"

Definitely worth the 5 minutes to watch. Succinct summation of what is being thrown away

ATTENTION New crowdsourced site collecting and sharing stories of public impact of research publicusaresearchbenefits.com Take a look and consider contributing. Let's make this as powerful as possible!

Well, somebody had to do it @nucleosomepolice.bsky.social 😬 Did you know that the nucleosome inspires the Millennium Falcon design? #Maythe4thBeWithYou #MayThe4th #MayTheFourthBeWithYou

www.nytimes.com/2025/04/28/o...

Cooper’s hawk in the park this am!

Carl Sagan when asked, "Are you a Socialist?"

We lost our beloved kitty Vector today. It was very sudden. Came home to find him barely conscious and rushed to the vet but he died in the car. Heartbroken 💔

“NIH will not only block new funding for the university, but also stop paying investigators working on all existing NIH projects.” That’s a lot of hard working people about to go without a paycheck, for reasons that have nothing to do with them

Happy Caturday!

“America shouldn’t take scientific progress in medicine, artificial intelligence, energy and more for granted. If the youngest, brightest minds aren’t soon reassured that the US can support their work — and that scientific inquiry will be protected from political interference — they will walk away.”

NEW: Sen. Todd Young (R-Ind.)& Trump's former NatSec Advisor Matt Pottinger make the case that funding for scientific R&D isn't a gift to academia. It's vital to U.S. national security, as China, the United States' primary strategic adversary, is already investing heavily in R&D. shorturl.at/PgUK0

“The NIH remains committed to upholding the principles of scientific integrity”….by rescinding the policy of scientific integrity 🙄 make it make sense….

A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.

Really important summary of the economic impact of cuts to federal funding

Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs. Find out how your community may be impacted. Explore more at SCIMaP: scienceimpacts.org a 🧵

Zoom meeting this morning and a colleague had two baby sheep in her office. Apparently they need feeding every 2 hours! She was requesting names. We came up with Wool Ferrell, Meryl Sheep, and Clint Beastwood. Any other suggestions? 😂🐏🐏

I worked across the pond from the EPA building at NiEHS. So many wonderful scientists and lovely people at the EPA. Can’t believe this 💩

They are cutting cancer research. They are cutting cancer research. They can deny it all they want, but they are cutting cancer research. These are the cuts being made the DoD CDMRP cancer funding mechanism www.fightcancer.org/sites/defaul...

We're so thrilled to finally share with you the published version of our CUT&Tag optimization and benchmarking paper "CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks" - out in @naturecomms.bsky.social today: www.nature.com/articles/s41...

A trio of domains has PHRF1, Each with unique work to be done. RING tags proteins for trash, PHD reads H3 in a flash, And SRI grips Pol II for fun! Awesome seminar by Kanishk Jain in our seminar series today! @chromajain.bsky.social

Finally! We have the answer to climate change denial and it comes from the greediest people on earth: Insurance companies. 🧪