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akshatsharma.bsky.social
Immunologist who leapfrogged from the private sector back to academia. Still hunting down TCRs for TCR-T therapy for cancer and autoimmunity. Actor by night. Lifter, also by night. GO BADGERS!
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Immunodominant epitope.

BUT I DID ALL THE STEPS! WTF! I was home for 5 days! 5 days; 5 steps! What do you mean "non-linear?" Can repeat? CAN REPEAT? Are you shitting me?!

What's an NK cell's cocktail of choice? A KIR Royale.

Happy Mental Health Awareness Month.

تمہاری بے رخی اک دن ہماری جان لے لے گی۔ قسم تم کو زرا سوچو کے دستور وفا کیا ہے۔ غم دنیا سے گھبرا کر تمہے دل نے پکارا ہے۔ کہاں ہو تم۔۔۔؟

But I was so looking forward to the inevitable documentary...

But, truly, a lovely paper with interesting implications for the role of the CHAC1-Notch axis in health and disease.

I just stared long and hard at the word "homogenous" in a grant I'm very slowly working on You never know these days: it could come back with "Dear Dr. Sharma: no homo."

Friends, if you or your colleagues are working on innate-like T cells, please consider submitting a manuscript or review to this special issue of Cells that I'm guest-editing: www.mdpi.com/journal/cell...

The one sempiternal thing about scientists is that we always come with receipts. You'll typically find them under a section titled "References."

Sadboi hours, empty weight room, Rockpile Athletics.

Meal prep pump. Evidently aggressive stirring will do it.

I curled 40lbs and am parched for attention.

www.nytimes.com/2025/04/18/b...

Such an improvement over Kr*st*e N**m's macabre selfies.

“It’s amazing that others in this room underwrote electing a man who, in the last week, single-handedly destroyed all of American science. It’s amazing how much good science you can destroy with $320 million and RFK Jr, very fast.” — Seth Rogen’s censored remarks presenting the Breakthrough Prize

Guys, I just want to do LFA-1 things and pull out TCRs. But it's, like, hard with, you know, everything...

Hilarious, obviously, but apparently Chef Sanjeev Kapoor has a restaurant in Palo Alto!

I'm viscerally disgusted by how many "self portraits" I produce. But, hey, man, the lighting was good... There's an urgency these days to get it all done. Get the grant, write the novella, find the fella, LFA-1... I'm worried I'm gonna die young. And, hey, man, the lighting was good...

Biomedical research. No-one's doing it like America.

A friend told me to try Scruff and also another app that had a militaristic name, and it was very upsetting. Why? I'll tell you why...

What will it take for y'all to acknowledge that influencers* are not journalists or medical professionals or therapists or scientists or economists or lawyers? *without the requisite training.

Bobby baby, Bobby bube, Robert darling, there's work out there to show that both mono- and multivalent COVID-19 vaccines elicited lovely, comparable T cell responses. Lots of evidence of this in the flu vaccine world, too. Why are you like this? Here: pmc.ncbi.nlm.nih.gov/articles/PMC...

Chat, what was it like planning your first senior author paper?

Comes with a 12-well-plate (tissue culture-treated for his pleasure), pipettes, pens,a flow cytometer, "Hateway's" Immunobiology (good try, I guess), 45 lb dumbbells (respectable, sorta), workout clothes, another flow cytometer and I think a tea cosy. Would you buy it, buy it, buy it?

عشق ایک، میر، بھاری پتھر ہے۔ یے کہاں ناتواں سے اٹھتا ہے؟ इश्क़ इक, मीर, भारी पत्थर है. यह कहाँ नातवां से उठता है? Love is a large rock, and unwieldy at that. How do you, feeble as you are, expect to carry it, my guy?

Anabolic lighting and, as my quads burned, I planned the most boring experiment in the world. BUT, the results will be exciting either way.

This is the energy I'm bringing to my TCR screen and the R21 that it shall spawn.

Planning an R21 and feeling kinda good about it....? Weird.

If I immediately started chanting the Hanuman Chalisa (which I have memorised, kinda), would they think I was speaking in tongues?