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alexis-verger.cpesr.fr
Molecular & structural biologist CNRS with a big respect for Transcription Factors, RNA Pol II & Mediator #CryoEM Advocating for #basicresearch #womeninSTEM #preprint Message in English or French. https://bsi-lille.cnrs.fr
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Some experiments are more important than others. Our annual campus BBQ

Postdoc post in my lab from Autumn this year @lsiexeter.bsky.social @exeter.ac.uk #Chromatin #StemCells #Enhancer #NeuralCrest #Transcription #CellFate #NuRDIsTheWord Apply and/or get in touch!

#alphafold 🙃🤣 X-ray structure of MED23 : 2018 AF2 : 2021 In this particular case (MED23), AF2 just accurately predicts what was already known experimentally 🫣 #justsaying

2nd Meeting on Epigenetics & Epigenomics - 24th - 26th September, Brussels 🇧🇪 Speakers Line-up looks fantastic including @adelmanlab.bsky.social @kjarmache.bsky.social @mariekeoudelaar.bsky.social @tinekelenstra.bsky.social @lucianodicroce.bsky.social www.xcellsconferences.com/epigenetics2...

A request to review an article from a journal I've never heard of Dated June 6, to be returned on the 11th.... with the full paper in Word format as an attachment to the mail.... 😵

Deep Learning of Proteins with Local and Global Regions of Disorder IDPForge, all-atom IDP ensembles and IDR disordered ensembles that maintains the folded domains paging @lindorfflarsen.bsky.social arxiv.org/abs/2502.113...

Hello Bluesky! We are happy to join this growing platform to further engage with the JMB community. We are looking forward to highlighting your impactful scientific discoveries and sharing news about upcoming issues and opportunities. Please follow us and stay tuned for some exciting updates!

Online now: Machine learning to predict de novo protein–protein interactions

Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀

Great to see this published @genesdev.bsky.social. Evidence that enhancers can activate a bystander gene in an adjacent TAD, and that cohesin facilitates this. @uoe-igc.bsky.social. pubmed.ncbi.nlm.nih.gov/40436628/

Kinetic control of mammalian transcription elongation cc @triggerloop.bsky.social www.biorxiv.org/content/10.1...

Very exciting work, congrats to all ! An intriguing regulation mechanism of kinase activity by one of its substrates in relation to #LLPS and interferonopathies

"Les gens qui cherchent", un documentaire qui nous plonge dans l’intimité des chercheurs du laboratoire @afmblab.bsky.social à Marseille france3-regions.franceinfo.fr/provence-alp...

Boltz-1x Chai-1 Protenix AF2 AF3 Unifold CombFold ESMFold D-I-TASSER RosettaFold All-Atom IgDesign RFantibody BindCraft RoseTTAFold2NA AFCluster AntiFold HighFold BioEmu DiffAb AbMPNN RFDiffusion HyperMPNN AntiBERTy AF-Traj AbGPT

Another tour-de-force by the Xu lab #cryoEM After the Pol II transcribing complexes (www.science.org/doi/10.1126/...), the Pol III transcribing complexes !!! www.nature.com/articles/s41...

Loïs Loïs Loïs!!!!!

BoltzDesign1 now available preprint : www.biorxiv.org/content/10.1... code: github.com/ullahsamee/B... colab: colab.research.google.com/github/yehli...

Bienvenue sur Bluesky @enseignementsup-recherche.gouv.fr #ESR

Reposting - please consider applying for a lab head role @wehi-research.bsky.social in Australia. It is a wonderful place to work, in a great country and with lovely colleagues. Clearly I’m biased on all of those counts. Please repost and/or apply!

I often send a little e-mail congratulating the corresponding author of a paper I really enjoyed reading. It's simple, quick and I think it's always nice to receive a positive message.

Combien de scientifiques ont quitté Twitter entre 2023 et 2025 ? Selon cette étude, 18% des universitaires sur 300 000 étudiés ont effectué une migration vers Bluesky. De plus, les chercheurs qui ont reconstruit leur réseau sur Bluesky restent significativement plus actifs et engagés. 1/2

🎉 New paper out in Science! In collaboration with Marc Therrien’s lab, we show how oncogenic BRAF mutants adopt a pre-active conformation, escaping auto-inhibition and driving RAS–ERK pathway activation in cancer. Proud to have contributed! #IRIC #CBMN @iecb.bsky.social @univbordeaux.bsky.social

The proposed R&D budget cuts will set the US back 30 years, jeopardize future innovation and sacrifice a whole new generation of scientists.

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Nice work by the Kurumizaka Lab in @natcomms.nature.com Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis www.nature.com/articles/s41...

Joyeux 70 ans à l' @ajspi.bsky.social et à tous les journalistes scientifiques

How women made history – and men took the credit. #womeninSTEM Apparently this book by Leonie Schöler (Beklaute Frauen : Stoeln women) is only in german. It would be great if it was translated into English (and/or French)

Très bon documentaire sur @artefr.bsky.social sur Rosalind Franklin avec du @matthewcobb.bsky.social dedans! www.arte.tv/fr/videos/11...

#ChooseChinaforScience www.nature.com/nature-index...

Now published! Big congrats to first author @gginell.bsky.social We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions. www.science.org/doi/10.1126/...

Dimanche direction Paris pour le session de Printemps du #CoNRS section 20 (future section 22). La der des der pour moi après 2 mandats. Un peu d'émotion, la tête pleine de beaux souvenirs de cette très enrichissante aventure humaine et scientifique au service de la communauté.

🚨Our new paper is online🚨 We use zero-distance⚡photo-crosslinking⚡to reveal direct protein-DNA interactions in living cells, enabling quantitative analysis of the DNA-interacting proteome on a timescale of minutes. #DNA #Chromatin #Proteomics www.cell.com/cell/fulltex...