Profile avatar
aliasgersalem.bsky.social
Associate Vice President for Research. Bighley Chair and Professor of Pharmaceutical Sciences. Views are my own. Science & Technology, Iowa City, IA salem.lab.uiowa.edu Joined 11/23/24
46 posts 405 followers 233 following
Prolific Poster

Iowa Now: UI professors Aliasger Salem and Mark Greiner receive new 5-year $2.85 million NIH grant to help prevent vision loss from corneal disease. now.uiowa.edu/news/2025/06...

Attention UIowa Summer Undergrad Researchers: On June 18th at 1:30pm in C44-A General Hospital, the undergraduate B.E.S.T. Researcher summer program will hold a panel discussion with myself, Ned Bowden, and Sarah Sapouckey on intellectual property and starting a company.

Just published: Cyclodextrin-Based Inclusion Complexes Improve the In Vitro Solubility and Pharmacokinetics of Ivacaftor Following Oral Administration in Mice. Nakhla et al. Link to article: rdcu.be/emoRw

The American Association of Pharmaceutical Scientists (AAPS) | @aapscomms National Biotechnology Conference in Boston #NBC2025 has started. The opening talk is from Dr. Nikhil Munshi, Professor of Medicine at Harvard University and Director at Dana-Farber Cancer Institute.

Just published: In situ treatment with a TLR9 agonist virus-like particle to promote immune responses against oral epithelial dysplasia progression. Xu et al. link.springer.com/article/10.1...

I’m delighted to share that our company S5G Therapeutics won the $50,000 first prize tonight in this year’s JPEC Innovation Challenge! We look forward to moving our therapy for surface ocular diseases into the clinic as our planned next steps.

Now published: The Heartland Environmental Alliance for Resilience & Transformation (HEART) – Improving the Lives and Livelihoods of People Across the Heartland Through Environmental Change Resilience Research, Education, and Outreach. doi.org/10.1029/2024...

The National Academy of Inventors has ranked the University of Iowa in the top 100 U.S. Universities granted U.S. utility patents through procurement of United States patents to protect the intellectual property of their accomplishments in innovation and invention.

The annual 2025 Society For Biomaterials meeting has been excellent. Mohammad Alnatour, Esraa Mohamed, Apurva Dusane, Ramkrishna Sen and Adam Salem all gave outstanding presentations. #SFB2025

The University of Iowa welcomes new members Drs Sandeep Laroia, Robert Philibert, Suresh Raghavan, Kristina Thiel, Molly Kucera and Maleeha Naseem to the local University of Iowa National Academy of Inventors chapter. Congratulations! research.uiowa.edu/news/2025/04...

Collaborative paper with Mark Greiner in press: Iron-Sulfur Clusters and Iron Responsive Element Binding Proteins Mediate Iron Accumulation in Corneal Endothelial Cells in Fuchs Dystrophy. Hartness et al. Investigative Ophthalmology & Visual Science. iovs.arvojournals.org/article.aspx...

Collaborative paper with Mark Greiner in press: Iron-Sulfur Clusters and Iron Responsive Element Binding Proteins Mediate Iron Accumulation in Corneal Endothelial Cells in Fuchs Dystrophy. Hartness et al. Investigative Ophthalmology & Visual Science. iovs.arvojournals.org/article.aspx...

I am delighted to share that I have received the 2025 Regents Award for Faculty Excellence. The award provides a state-wide forum in which the excellence of faculty members is recognized and shared with colleagues from other Regent institutions. now.uiowa.edu/news/2025/04...

My visit to Virginia Commonwealth University School of Pharmacy today was excellent. The visit was also an excellent opportunity for our new $13 million VCU-Iowa program project team (including Drs Sarkar and Fisher) focused on treating liver cancer to connect and plan next steps.

Tomorrow is One Day for Iowa, and University of Iowa Core Equipment Facilities needs you! Give to University of Iowa @UIowaResearch Core Equipment Facilities 1dayforiowa.org/VPR25

Im looking forward to presenting my research at VCU School of Pharmacy this Friday, (03/28). My favorite invitations to speak are consistently the ones that come from the students and I'm grateful to the AAPS VCU student chapter for planning the visit.

Read about recent work on how circulating tumor DNA in blood samples can predict which colorectal cancer patients should and should not get chemotherapy from my good friend, colleague and collaborator Dr. Pashtoon Kasi. www.cancer.gov/news-events/...

Collaborative paper in press: Astrocyte elevated gene-1 (AEG-1) in myeloid cells is a key driver for the development of chemotherapy-induced peripheral neuropathy. authors.elsevier.com/c/1ko~33AAzz...

The John Pappajohn Entrepreneurial Center at U Iowa plays a critical role in promoting entrepreneurship and supporting start up companies. This includes running the NSF I-Corps program that I currently help to lead. Read more about my own JPEC experience here: iowajpec.org/news/2025/03...

The University Lecture Committee organized an event: “An evening with Dr. Siddhartha Mukherjee: The Art of Cancer Research” on March 4th. He read from his book “The Emperor of All Maladies: A Biography of Cancer” and shared his thoughts on the current state of cancer research.

Selenium is an essential nutrient named after the Greek goddess of the Moon − crucial to health, it may help prevent and treat cancer. Click on the link below to learn more: theconversation.com/selenium-is-...

In press: Gene‑activation of surface‑modified 3D printed calcium phosphate scaffolds. Noah Zach Laird, Pornpoj Phruttiwanichakun, Esraa Mohamed, Timothy Acri, LR Jaidev Chakka, Aliasger K. Salem. BMC Chemistry. 2025. rdcu.be/eaP2H @UIPharmacy

I am pleased to share that myself, Mark Greiner (University of Iowa) and Sara Thomasy (UC Davis) have been awarded a new National Institutes of Health (National Eye Institute) R01 grant for $2.85 million focused on "Modulating Ferroptosis in Fuchs Endothelial Corneal Dystrophy".

Read my latest article discussing indirect costs on @NIH grants: "How much does scientific progress cost? Without government dollars for research infrastructure, breakthroughs become improbable." in The Conversation. theconversation.com/how-much-doe...

Indirect costs are how the government supports research infrastructure for the nation and are critical to all research activities. They cover real expenses, including buildings and labs, equipment, and staff who support our research. The figure below shows what indirects cover

Collaborative study led by Dr. Yousef Zakharia in press: Phase I Clinical Trial of High Doses of Seleno-L-methionine in Combination with Axitinib in Patients with Previously Treated Metastatic Clear Cell Renal Cell Carcinoma. doi.org/10.1158/1078...

In press: 3D bioprinted ferret mesenchymal stem cell-laden cartilage grafts for laryngotracheal reconstruction in a ferret surgical model. McMillan et al. Biomaterials Science. pubs.rsc.org/en/content/a...

Read the following article: Medical research depends on government money – even a day’s delay in the intricate funding process throws science off-kilter. This article describes the rigorous process by which NIH make research project grant funding decisions. theconversation.com/medical-rese...

In proud to share that Esraa Mohamed has been featured in this year's University of Iowa Dare to Discover Campaign. Esraa is developing therapies to counteract toxic gas exposures. Learn more at the following page: dare.research.uiowa.edu/mohamed-esraa/

Meet phosphine, a gas commonly used for industrial fumigation that can damage your lungs, heart and liver. theconversation.com/meet-phosphi...

University of Iowa Center for Biocatalysis and Bioprocessing approved for $1 million Strategic Infrastructure Program grant. corridorbusiness.com/ieda-board-a...

Read about our recent collaborative work developing treatments for corneal diseases: "Iowa researchers study role of genes in eye disease that leads to vision loss" now.uiowa.edu/news/2025/01...

In press: Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: mechanisms and therapeutic potential. Cancer Treatment and Research Communications. Rataan et al. doi.org/10.1016/j.ct...

Research Scientists Positions at Abscora Inc Available: See more details at: www.linkedin.com/feed/update/... #Immunology #Immunotherapy #Cancer #Scientist #Jobs #PhD

Consider submitting an abstract to the Iowa PFAS Conference (April 15–16, 2025): lnkd.in/gy-iQZVX The abstract deadline is February 15, 2025 and submission details can be found here: lnkd.in/g8KpG88M

Dr. Michael Wendt will be presenting his research on "Targeting Cellular Plasticity in Metastatic Breast Cancer" at the University of Iowa College of Pharmacy on Jan 14th 2024.

Season’s greetings and happy holidays from the Salem Research group at the University of Iowa College of Pharmacy

Microplastics: a systematic review of health harms pubs.acs.org/doi/10.1021/... open-access "Microplastics are “suspected” to harm human reproduction and digestive and respiratory health, with a suggested link to colon cancer." open-access

Super interesting! Once itaconate enters the cancer cell, it activates the NRF2 pathway, which induces the expression of SLC7A11, allowing cystine uptake and leading to ferroptosis resistance.

Iowa-Nebraska Collaboration Moves to Stage Two of NSF Engines Program. The University of Iowa is committed to bringing research and discovery into the service of Iowans, improving lives through technological advancement and economic vitality. research.iastate.edu/2024/12/06/i...

The 19th International Symposium on Recent Advances in Drug Delivery will be held at the University of Utah on February 25-28, 2025. The program agenda is now published online: na.eventscloud.com/ehome/radds2...

The Immune Response Source: Big Picture & Wellcome Trust HD: www.tes.com/teaching-res...

In case some mentors may want to read this. #Nature #PhD #scisky #student #mentor Source: www.researchgate.net/publication/...

Check out this job: Tenure-Track Faculty Position at Pharmaceutical Sciences, The College of Pharmacy, in collaboration with BioInnovations in Brain Cancer Initiative (BIBC) program

📈 Trending Article in PNAS One of the most-viewed PNAS articles in the last week is “A small-molecule carrier for the intracellular delivery of a membrane-impermeable protein with retained bioactivity.” www.pnas.org/doi/10.1073/... For more trending articles, visit ow.ly/Me2U50SkLRZ.

The chlorine dioxide leak in Weslaco highlights the continuing accidental chemical exposures that occur in the USA. As I mention in this news video, any adverse effects to those chemicals are dependent on dose and duration. NIH is funding our development of therapies. www.krgv.com/news/weslaco...