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arielkaplan.bsky.social
Single molecule biophysics, Optical Tweezers, Chromatin, Transcription, Polymerases, Helicases Associate Professor, Technion-Israel Institute of Technology https://kaplan.net.technion.ac.il/
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Oldies but Goldies. from 2007. Light-powering Escherichia coli with proteorhodopsin www.pnas.org/doi/10.1073/...

submitted 7 days ago • 1 comment

@arielchazan.bsky.social @galitzlil.bsky.social

submitted 17 days ago • 0 comments

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

submitted 17 days ago • 464 comments

open.substack.com/pub/joshuasw...

submitted 17 days ago • 0 comments

www.nature.com/articles/d41...

submitted 17 days ago • 0 comments

Nice work by the Kurumizaka Lab in @natcomms.nature.com Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis www.nature.com/articles/s41...

submitted 19 days ago • 2 comments

1/ New preprint! How do transcription factors (TFs) use intrinsically disordered regions (IDRs) to find their target sites? www.biorxiv.org/content/10.1... #TranscriptionFactors #IDPs #SingleMolecule #Biophysics

submitted 21 days ago • 1 comment

Super cool work on the function of intrinsically disordered regions in regulating transcription factor DNA binding.

submitted 20 days ago • 1 comment

The energy landscape of a single disordered protein (tau) and the impact of PTMs is resolved. An important step to understanding the function and dysfunction of disordered proteins from their conformational ensemble. Not yet peer reviewed. www.biorxiv.org/content/10.1...

submitted 20 days ago • 0 comments

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

submitted 21 days ago • 6 comments

1/ New preprint! How do transcription factors (TFs) use intrinsically disordered regions (IDRs) to find their target sites? www.biorxiv.org/content/10.1... #TranscriptionFactors #IDPs #SingleMolecule #Biophysics

submitted 21 days ago • 1 comment

And, again, WHERE IS #BIGPHARMA in defending #basicscience? laying low? playing dead? Waiting it out? Do SOMETHING! SPEAK UP! Use your gigantic lobbying machine to defend us instead of peddling your wares and increasing your profits. Or do you think highly trained workforce grows on trees?

submitted 46 days ago • 6 comments

Wow - this is also the cofactor for the lyase activity of Cyp17A1 - required for production of androgens from pregnenolone/progesterone.

submitted 119 days ago • 0 comments

www.cell.com/molecular-ce...

submitted 162 days ago • 0 comments

Congratulations to Prof. Nabieh Ayoub on receiving the Award for Outstanding Excellence in Teaching for the Spring Semester of 2024 biology.technion.ac.il/en/congratul...

submitted 166 days ago • 0 comments

Did you know that there is an enzyme called ATAC, which is not related to ATAC-seq? :) academic.oup.com/nar/advance-... This paper reports a very interesting finding that ATAC and SAGA increase TF binding to DNA target sites on nucleosome by an order of magnitude independent of histone acetylation

submitted 191 days ago • 0 comments

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

submitted 196 days ago • 467 comments

Best practice mass photometry: A guide to optimal single molecule mass measurement https://www.biorxiv.org/content/10.1101/2024.12.03.624087v1

submitted 195 days ago • 0 comments

As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...

submitted 202 days ago • 2 comments