babak-a.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Allowing Netanyahu to drag us into another endless war in the Middle East would be a catastrophic error by President Trump and Republicans in Congress. Every lawmaker needs to ring the alarm against U.S. military action in Iran. Only Congress has the authority to declare war.

submitted 1 day ago • 127 comments

I wrote a review of a recent paper on false discovery and multiple testing correction. liorpachter.wordpress.com/2025/06/16/r...

submitted 2 days ago • 7 comments

Less than 200 years ago, one in three Dutch children died before the age of five

submitted 12 days ago • 5 comments

In case you needed a smile this Tuesday: 10-month-old baby KJ, who received a bespoke gene-editing therapy after a six month scientific sprint - "graduated" from the hospital @childrensphila.bsky.social today and went HOME! YAY SCIENCE! Here's his story: wapo.st/451ZQjT

submitted 15 days ago • 6 comments

Wow! What a way to surrender your scientific advantage just so that #MAHA can keep needles away from children. #NIH #NASA #NSF

submitted 18 days ago • 5 comments

We're thrilled to introduce PromoterAI — a tool for accurately identifying promoter variants that impact gene expression. 🧵 (1/)

submitted 20 days ago • 1 comment

Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.

submitted 21 days ago • 1 comment

My father worked in a tire factory in Appalachia. Friends and family in the military. Used to vote Republican. Got into college on a diversity program for the underprivileged. Ended up a Harvard professor. And now my funding is terminated because we're trying to stick it to the elites.

submitted 22 days ago • 4 comments

NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.

submitted 28 days ago • 36 comments

Such a wonderful little tool! A Jupyter Lab run entirely on your browser!

submitted 22 days ago • 0 comments

GSK paid $600M to access just the GWAS summary statistics a few years ago. In contrast, Regeneron paid only $256M for everything: summary stats, individual-level genotypes and phenotypes (over 10 million people), therapeutic programs, and leads. Unbelievable. www.biospace.com/business/reg...

submitted 30 days ago • 0 comments

Another mind-blowing milestone! What we do in biotech in academia and industry matters; science matters.

submitted 34 days ago • 0 comments

Really excited to see this published! From observations we made in our lab… to a blood test that works in real life scenarios… all thanks to the many scientists, ML researchers and engineers at @exai.bio who have worked on bringing this to the clinic. Kudos @babak-a.bsky.social and the team!

submitted 34 days ago • 0 comments

💥New Publication Alert in Clinical Cancer Research💥 We are thrilled to announce our latest publication on our novel RNA and generative AI liquid biopsy platform for early colorectal cancer detection. #EarlyDetection #LiquidBiopsy #RNA Read the full publication here: aacrjournals.org/clincancerre...

submitted 34 days ago • 0 comments

This is truly a monumental day for me and the @exai.bio team! We are presenting a cell-free RNA-based colorectal cancer test, validated on an independent cohort, with 80% Stage I sensitivity at 90% specificity. A long-term project led by @amir-r.bsky.social aacrjournals.org/clincancerre...

submitted 34 days ago • 1 comment

Exai Bio presented new data demonstrating the power of its RNA and AI based liquid biopsy platform to detect colorectal cancer. Stage I sensitivity in an independent cohort was 80%, exceeding other blood based approaches. Thanks to Amir Momen-Roknabadi for representing Exai Bio at #AACR25!

submitted 49 days ago • 1 comment

I would take "relapse" or "regression" and "blunder" over "error" any day!

submitted 55 days ago • 0 comments

1/ It has been a privilege to have the opportunity of contributing to Exai-1. Shout out to my co-first author, Aiden Sabadbi, and my amazing colleagues @exai.bio, particularly @fhormozd.bsky.social, @babak-a.bsky.social, and @genophoria.bsky.social who led the effort.

submitted 78 days ago • 1 comment

Super excited to share that our paper on a multi-modal cell-free RNA foundation model is out! A fantastic collaboration with @genophoria.bsky.social, @fhormozd.bsky.social and the @exai.bio team!

submitted 78 days ago • 1 comment

Joining forces with the legendary @babak-a.bsky.social, @fhormozd.bsky.social, and @mkarimzadeh.bsky.social to bring you Exai-1; a multi-modal cell-free RNA foundation model for blood surveillance and liquid biopsy applications. Kudos to the broader @exai.bio team! www.biorxiv.org/content/10.1...

submitted 78 days ago • 1 comment

US women deserve better

submitted 79 days ago • 80 comments

Utah banned fluoridated water: water with 0.7 grams of fluoride for every 1,000,000 grams of water. The claim? It’s harmful. The reality? It isn’t ⬇️ An adult would need to consume 357 LITERS of that water A DAY to have a possible risk of adverse effects from fluoride. 1/

submitted 82 days ago • 113 comments

#Thisweeksfiddler from @xaqwg.bsky.social asked: if you're randomly situated on a semicircular island, what is your expected distance from the coast? After a lot of geometry, calculus and algebra (plus a bit of help from WolframAlpha) I got a surprisingly simple answer. tinyurl.com/fiddler140325

submitted 93 days ago • 0 comments

I bought a Tesla because it was fast like a rocket ship. But now every time I drive it, I feel like a rolling billboard for a man dismantling our government and hurting people. So Tesla, you’re fired! New ride coming soon.

submitted 96 days ago • 4060 comments

So proud to see our work on machine learning + enzyme design just published! www.cell.com/cell-systems... Fun collaboration between Google X, DeepMind, and Triplebar that we hope can be a template for integrating ML and high throughput screening in protein engineering

submitted 98 days ago • 2 comments

Avoid physical gift cards—they're often compromised, and funds can be stolen instantly after loading. In one case, 20% of a child's birthday gift cards were already drained. If necessary, opt for electronic gift cards. Check out the story below. www.nbcbayarea.com/investigatio...

submitted 102 days ago • 0 comments

Awesome summary of the field. An important point is to separate the design method from the oracle model being used. Sometimes, people say they're proposing a new design method but mean a cool new oracle model. Modelling and design of transcriptional enhancers www.nature.com/articles/s44...

submitted 107 days ago • 1 comment

"I was relieved that it was just the flu and felt that she would be okay." A father learns the devastating truth about influenza. www.voicesforvaccines.org/trust-me-you...

submitted 108 days ago • 6 comments

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

submitted 109 days ago • 63 comments

Finally, someone who gets RNA. xkcd.com/3056/

submitted 111 days ago • 0 comments

This is what science does. It is truly an accumulation of decades of basic and translational research, funded both publicly and privately.

submitted 118 days ago • 0 comments

Attention Attention Attention If anyone knows clinicians or patients who have knowledge of pediatric patients with the very rare cancer interdigitating dendritic cell sarcoma (IDCS) or other (non-LCH) dendritic or histiocytoc sarcomas please contact Sri

submitted 130 days ago • 0 comments

Please help Sri if you can, and share and spread the word.

submitted 130 days ago • 0 comments

We worked for months with USAID to build an $85,000,000 project to end TB in two regions of the Philippines. The project is funded by private money, the Philippine government, and matching USAID funds. It could provide a blueprint for eliminating TB worldwide--except it's...not happening.

submitted 135 days ago • 490 comments

There's a wide range of "ultra-processed foods." A recent Nature Foods paper zoomed in on this www.nature.com/articles/s43... and the graph rankings are shown below from @sciam.bsky.social www.scientificamerican.com/article/whic...

submitted 138 days ago • 12 comments

Please consider donating to this GoFundMe for Dr. Sheila Colla who is facing a rare type of cancer: www.gofundme.com/f/support-sh... #WomenInSTEM

submitted 143 days ago • 0 comments

Check out our new & improved V2 manuscript for RiboNN, with new analyses to further sharpen the results!! www.biorxiv.org/content/10.1...

submitted 150 days ago • 0 comments

My thesis work on active machine learning to model regulatory DNA is now out in Cell Systems! We answer the question: When you can synthesize any DNA sequence you want, how do you decide which ones are worth testing? www.sciencedirect.com/science/arti...

submitted 162 days ago • 3 comments