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Analysis of 3'-seq data from multiple E. coli studies identifies diverging results sets and raw data characteristics despite similar collection conditions https://www.biorxiv.org/content/10.1101/2025.06.12.658996v1

submitted 40 minutes ago • 0 comments

Integrating structural homology with deep learning to achieve highly accurate protein-protein interface prediction for the human interactome https://www.biorxiv.org/content/10.1101/2025.06.09.658393v1

submitted 41 minutes ago • 0 comments

A fast TMT-based proteomic workflow reveals neural enrichment in neurospheres of hiPSC-derived neural stem cells https://www.biorxiv.org/content/10.1101/2025.06.09.658417v1

submitted 1 hour ago • 0 comments

CSLAN: Cross-Species Latent Alignment Network for Trauma-Related Cell-Type Classification https://www.biorxiv.org/content/10.1101/2025.06.09.655966v1

submitted 3 hours ago • 0 comments

Biologically Guided Variational Inference for Interpretable Multimodal Single-Cell Integration and Mechanistic Discovery https://www.biorxiv.org/content/10.1101/2025.06.10.657924v1

submitted 3 hours ago • 0 comments

Deacon: fast sequence filtering and contaminant depletion https://www.biorxiv.org/content/10.1101/2025.06.09.658732v1

submitted 3 hours ago • 0 comments

Multiplets in scRNA-seq data: extent of the problem and efficacy of methods for removal https://www.biorxiv.org/content/10.1101/2025.06.09.658708v1

submitted 3 hours ago • 0 comments

Knowledge Graph-Based Framework for Detecting Horizontal Gene Transfer Events Driving Antimicrobial Resistance https://www.biorxiv.org/content/10.1101/2025.06.09.658534v1

submitted 6 hours ago • 0 comments

PPIKB: A Comprehensive Knowledge Base and Analysis Platform for Protein Peptide Interactions Based on Literature and Patents https://www.biorxiv.org/content/10.1101/2025.06.09.658607v1

submitted 6 hours ago • 0 comments

Cross-Platform Omics Pipeline for Integrated Transcriptomics https://www.biorxiv.org/content/10.1101/2025.06.11.659031v1

submitted 9 hours ago • 0 comments

Application and Characterization of the Multiple Instance Learning Framework in Flow Cytometry https://www.biorxiv.org/content/10.1101/2025.06.10.658646v1

submitted 11 hours ago • 0 comments

Regularized Deep Neural Networks for Combining Heterogeneous Features of Peptides in Data Independent Acquisition Mass Spectrometry https://www.biorxiv.org/content/10.1101/2025.06.09.658564v1

submitted 11 hours ago • 0 comments

Identification of Novel Marine-based Inhibitors against Tetracycline Destructase in Acinetobacter Baumannii using Computational Approaches https://www.biorxiv.org/content/10.1101/2025.06.08.658539v1

submitted 23 hours ago • 0 comments

Targeting Listeria virulence-regulon glutathion-cavity by evolutecas https://www.biorxiv.org/content/10.1101/2025.06.09.658548v1

submitted 23 hours ago • 0 comments

Better antibodies engineered with a GLIMPSE of human data https://www.biorxiv.org/content/10.1101/2025.06.08.658113v1

submitted 1 day ago • 0 comments

Distinct Transcriptomic Biomarkers and Pathways Associated with Cardiovascular and Neurovascular Dysregulation in Long COVID-19 Brain Fog https://www.biorxiv.org/content/10.1101/2025.06.10.656785v1

submitted 1 day ago • 0 comments

SARS-CoV-2-induced dysregulation in ADAR editing patterns persists post viral clearance in individuals with mild COVID-19 https://www.biorxiv.org/content/10.1101/2025.06.09.658648v1

submitted 1 day ago • 0 comments

Insilico investigation of novel Plasmodium Falciparum Glycogen Synthase Kinase(pfGSk3β) inhibitors for the treatment of malaria infection https://www.biorxiv.org/content/10.1101/2025.06.07.658456v1

submitted 1 day ago • 0 comments

Gender-specific MetS prediction using pathophysiological determinants: Beyond diagnostic constraints https://www.biorxiv.org/content/10.1101/2025.06.10.658812v1

submitted 1 day ago • 0 comments

Detect de novo expressed ORFs in transcriptomes withDESwoMAN https://www.biorxiv.org/content/10.1101/2025.06.10.658796v1

submitted 1 day ago • 0 comments

A Generalizable Machine Learning Model for Early Detection of Hepatocellular Carcinoma Using Bisulfite Sequencing Data https://www.biorxiv.org/content/10.1101/2025.06.09.658649v1

submitted 2 days ago • 0 comments

TaxonReportViewer: Parsing and Visualizing Taxonomic Hierarchies in Metagenomic Datasets https://www.biorxiv.org/content/10.1101/2025.06.07.658440v1

submitted 2 days ago • 0 comments

Cut-Detector: A Tool for Automated Temporal Analysis of Late Cytokinetic Events https://www.biorxiv.org/content/10.1101/2025.06.06.658046v1

submitted 2 days ago • 0 comments

Decoding PDI diversity: insights into structure, domains, and functionality in sorghum https://www.biorxiv.org/content/10.1101/2025.06.06.658324v1

submitted 2 days ago • 0 comments

PhenoGraph: A Multi-Agent Framework for Phenotype-driven Discovery in Spatial Transcriptomics Data Augmented with Knowledge Graphs https://www.biorxiv.org/content/10.1101/2025.06.06.658341v1

submitted 2 days ago • 0 comments

Monalisa: An Open Source, Documented, User-Friendly MATLAB Toolbox for Magnetic Resonance Imaging Reconstruction https://www.biorxiv.org/content/10.1101/2025.06.06.658299v1

submitted 2 days ago • 0 comments

Boosting AlphaFold Protein Tertiary Structure Prediction through MSA Engineering and Extensive Model Sampling and Ranking in CASP16 https://www.biorxiv.org/content/10.1101/2025.06.06.658338v1

submitted 3 days ago • 0 comments

AI-Driven Identification and Validation of RXFP1 as a CML Biomarker Using Gene Expression and Integrated GUI Tools https://www.biorxiv.org/content/10.1101/2025.06.06.658261v1

submitted 3 days ago • 0 comments

Identification of reactive CpGs and RNA expression in early COVID-19 through cis-eQTM analysis reflecting disease severity and recovery https://www.biorxiv.org/content/10.1101/2025.06.09.658549v1

submitted 3 days ago • 0 comments

SMART: An Integrated Platform Revolutionizing Cryo-Electron Microscopy Workflow from Data Acquisition to Atomic Modeling https://www.biorxiv.org/content/10.1101/2025.06.05.657588v1

submitted 3 days ago • 1 comment

Uncovering Heterogeneous Effects via Localized Feature Selection https://www.biorxiv.org/content/10.1101/2025.06.03.657761v1

submitted 3 days ago • 0 comments

Evaluating the Influence of Disease-Gene Associations in the Significance of Disease Modules through the lens of Network Medicine https://www.biorxiv.org/content/10.1101/2025.06.05.657982v1

submitted 3 days ago • 0 comments

Harnessing Immunoinformatic for HIV-2: Multi-Epitope Vaccine Design Targeting the env Protein (CAA28914.1) https://www.biorxiv.org/content/10.1101/2025.06.06.658249v1

submitted 3 days ago • 0 comments

{Psi}-Atlas: an integrated atlas for pseudouridine epitranscriptome https://www.biorxiv.org/content/10.1101/2025.06.06.656536v1

submitted 3 days ago • 0 comments

PLIERv2: bigger, better and faster https://www.biorxiv.org/content/10.1101/2025.06.05.658122v1

submitted 3 days ago • 0 comments

Ish: SIMD and GPU Accelerated Local and Semi-Global Alignment as a CLI Filtering Tool https://www.biorxiv.org/content/10.1101/2025.06.04.657890v1

submitted 3 days ago • 0 comments

PIVOT: an open-source tool for multi-omic spatial data registration https://www.biorxiv.org/content/10.1101/2025.06.08.658506v1

submitted 3 days ago • 0 comments

Bridging Genomics and Clinical Medicine: RSVrecon Enhances RSV Surveillance with Automated Genotyping and Clinically-important Mutation Reporting https://www.biorxiv.org/content/10.1101/2025.06.03.657184v1

submitted 3 days ago • 0 comments

Features fusion or not: harnessing multiple pathological foundation models using Meta-Encoder for downstream tasks fine-tuning https://www.biorxiv.org/content/10.1101/2025.06.05.657960v1

submitted 3 days ago • 0 comments

tidypopgen: Tidy Population Genetics in R https://www.biorxiv.org/content/10.1101/2025.06.06.658325v1

submitted 3 days ago • 0 comments

Enhancing CYP450-Ligand Binding Predictions: A Comparative Analysis of Ligand-Based and Hybrid Machine Learning Models https://www.biorxiv.org/content/10.1101/2025.06.05.658010v1

submitted 3 days ago • 0 comments

Quantifying Protein-Protein Interaction with a Spatial Attention Kinetic Graph Neural Network https://www.biorxiv.org/content/10.1101/2025.06.04.657832v1

submitted 3 days ago • 0 comments

A simple workflow to identify novel Small Linear Motif (SLiM)-mediated interactions with AlphaFold https://www.biorxiv.org/content/10.1101/2025.06.04.657817v1

submitted 3 days ago • 0 comments

Identification of mitochondria and macrophage activation related hub genes in sarcopenia https://www.biorxiv.org/content/10.1101/2025.06.04.657824v1

submitted 3 days ago • 0 comments

Prioritization of Potential Drugs Through Pathway-Based Drug Repurposing and Network Proximity Analysis https://www.biorxiv.org/content/10.1101/2025.06.05.658004v1

submitted 3 days ago • 0 comments

ImmunoFusion: A Unified Platform for Investigating RNA-seq-Derived Gene Fusions in Cancer and Immunotherapy https://www.biorxiv.org/content/10.1101/2025.06.05.658082v1

submitted 3 days ago • 0 comments

scMetaIntegrator: a meta-analysis approach to paired single-cell differential expression analysis https://www.biorxiv.org/content/10.1101/2025.06.04.657898v1

submitted 3 days ago • 0 comments

Mechanistic insights into Down syndrome comorbidities via convergent RNA-seq and TWAS signals https://www.biorxiv.org/content/10.1101/2025.06.05.658129v1

submitted 3 days ago • 0 comments

Machine learning can identify orphans that have diverged into the ''twilight zone'' of sequence similarity https://www.biorxiv.org/content/10.1101/2025.06.06.658213v1

submitted 3 days ago • 0 comments

OmnibusX: A unified platform for accessible multi-omics analysis https://www.biorxiv.org/content/10.1101/2025.06.06.658217v1

submitted 3 days ago • 0 comments