crisprguru.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

A tailor-made CRISPR therapy corrected a deadly genetic mutation in a baby. Details 👉 tinyurl.com/44v4y4y8 Key Messages: -Such breakthroughs are only possible because of years of investment in basic research. -Animal studies using transgenic mice are crucial to ensure therapies are safe & effective.

submitted 26 days ago • 0 comments

I’m sure at some point, everyone has needed painkillers Here’s a story from @jeremymberg.bsky.social that shows how decades of research contribute to the development of drugs, from painkillers to life-saving chemotherapies So, how many FDA-approved drugs have gone through years of research? >20,000😲

submitted 110 days ago • 0 comments

Many of us, especially those who left our home countries to pursue bigger dreams, face many struggles in our careers. We often hide these struggles. But silence comes at a high cost. Here is an insightful article on this topic tinyurl.com/2s5z38f5 More thoughts here: www.linkedin.com/feed/update/...

submitted 150 days ago • 0 comments

Two interesting articles were published in Nature today. They highlight the complexity and promise of heritable human genome editing. www.nature.com/articles/s41... www.nature.com/articles/d41... They are definitely worth reading. My (brief) thoughts are in here: www.linkedin.com/feed/update/...

submitted 155 days ago • 0 comments

Well said!

submitted 155 days ago • 0 comments

I attended the first SynBYSS International conference earlier this month, and it was unlike any other conference I’ve been to. Here is why… www.linkedin.com/feed/update/... www.jcvi.org/events/synbyss

submitted 164 days ago • 1 comment

A great article written by NIH Scientific Review Officers about how to write successful grant applications. I picked up many useful tips from reading this article. I am sure you too will!! www.pnas.org/doi/10.1073/...

submitted 165 days ago • 0 comments

submitted 169 days ago • 0 comments

Yes, it should be BlueSky everywhere!

submitted 169 days ago • 0 comments

Sunday breakfast!

submitted 186 days ago • 1 comment

I am a scientist. Just two starter packs was enough to find everyone I wanted to be connected to. bsky.app/starter-pack... bsky.app/starter-pack... I found everyone within 7 days! It had taken me 7 years at the other place.

submitted 191 days ago • 0 comments

This is awesome, folks! I will NOT post or re-post papers on the other site anymore. It will be ONLY on @bsky.app from now onwards! bsky.social/about/blog/1...

submitted 191 days ago • 0 comments

Bluesky Tricks Did you know when sharing a 🔗 in a post but you're running out of characters there's a trick Paste the 🔗 Wait a sec until the picture of the web page (or bluesky post/feed/starter pack) appears below then simply delete the typed 🔗! The picture remains & is a hyperlink

submitted 192 days ago • 2 comments

For those interested in "Genome editing and CRISPR technologies": (if you are new here at Bluesky), here are the two starter packs... bsky.app/starter-pack... bsky.app/starter-pack...

submitted 192 days ago • 0 comments

Sunday Lunch... Rice and lentil curry, and some ghee! How its made? See video in the reply!

submitted 193 days ago • 2 comments

In early 2000s @jshendure.bsky.social came up with a concept called "DNA Typewriter"-to type words into genomes for use as barcodes to study cellular activities & cell-fate. They couldn't test the idea then, but CRISPR tool helped 20 yrs later Here is a great review about the field shorturl.at/Uyh70

submitted 193 days ago • 1 comment

CRISPR cuts genomes but addition of new DNA strings at the cut sites, aka HDR, is an outcome of interplay between DNA repair proteins. DNA-PKc inhibitors are known to enhance HDR. But this new paper from J Corn (bskyless) shows large-scale genomic alterations if inhibitors are used shorturl.at/NXsTE

submitted 193 days ago • 1 comment

"RASAM" a very creative acronym(!) for a molecular technique developed by @vram142.bsky.social and his team! www.cell.com/cell/fulltex...

submitted 194 days ago • 0 comments

The CRISPR-Cas9 tool knows ONLY to cut a genome at a specific spot. It does not know how to edit the cut site the way we would like it to be. Genome Editors rely on the complete mercy of the cellular DNA repair machinery, to find a genome with a desired edit.

submitted 194 days ago • 1 comment

Thanksgiving dinner.

submitted 196 days ago • 1 comment

This article by @itaiyanai.bsky.social is a great read. The link to the article is here... genomebiology.biomedcentral.com/articles/10....

submitted 198 days ago • 0 comments

Not everyday is great for anyone. For me, cooking helps me feel good in general and it helps me beat stress. I may post my cooking videos or pictures of my meals, occasionally. Ginger Cardamom Tea👇 Have a great week!

submitted 199 days ago • 0 comments

Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling go.nature.com/4hXER5O

submitted 203 days ago • 0 comments

Did you know? If you decide to leave #blueskysocial, you can take all your digital bags (followers and all!!) with you! www.youtube.com/watch?v=Psag...

submitted 200 days ago • 0 comments

In my opinion, this paper is A MUST READ for anyone who writes grant proposals. I am sure you will agree that 'reading this entire paper was totally worth your time.'