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drsanil.bsky.social
Psychiatrist | Educator | Neuroscience Enthusiast | Exploring the intersection of biology, psychology & human behaviour | Sharing insights, ideas & stories to simplify complexity.
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New video 🚨👉You're Not Treating a Label- You're Treating a Human ✅ Give me 5 minutes-and it might change the way you approach treatment. If you don’t define the targets, you’re flying blind- no matter how “right” the diagnosis seems. Here’s how to change that 👇 Video 👉 youtu.be/0TINiQeot3M?si…

🚨 NEW - ADHD and Non Stimulants 🚀 ADHD meds = dopamine-spiking stimulants. But is it hiding a long-term price? I break down the non-stimulant options- from atomoxetine to a med that slashed symptom scores by ~50%. Video 👉 youtu.be/I0JGVNWTZsM?si… *General education only #adhd #stimulants

Antidepressants are just like heroin.🚨 That’s the claim. And it’s dead wrong - in two completely different ways. I break it down: – What real addiction is – Why SSRI withdrawal ≠ addiction – The dangers of lazy science Video 👇 youtu.be/_kVPN6goeTw

The Overlooked Reason ADHD Treatment Fails - Fix This First youtu.be/5giC7Hh0AmA

New Video🚀 This topic often flies under the radar yet frequently arises in clinical practice, particularly in addiction & sexual health settings. Chemsex involves complex intersections of trauma, stigma, substance use, and mental health. Clinicians should be aware. 👇 Video : youtu.be/kdbS22vBYzA

New video : Exploring ‘The Substance’ through a psychodynamic lens: 👉The split self and identity diffusion 👉Role absorption 👉Repetition compulsion 👉An insight into borderline personality organisation 👉Cyclical Psychodynamics youtu.be/OLp9zocvcQ8

A visual guide to metabolic switching 👉https://youtu.be/NDV-AlCfBYc?si=4h1welf3sbg_jeow

New video on YT I cover : 1. The gut-brain connection 2. Inflammatory vs. anti-inflammatory diets 3. Evidence for Mediterranean & ketogenic diets 4. Nutrients for serotonin, dopamine production 5.Practical steps to ‘support your brain’ with food youtu.be/TPY-rB4N3V0

🧠 What Happens to Your Brain Without Sleep?🚨 3 Days Without Sleep—Here’s What Happens Next 👉 youtu.be/NY4oNQd-xeY

15 Commandments of Psychopharmacology 🚀 Textbooks taught me psychopharmacology-UNTIL I stepped into real-world practice as a consultant psychiatrist. 🚨 Here’s what experience taught me that textbooks don’t (or can’t).

🚀 New YT video out! 👉 youtu.be/q_5hZUnmsI4?si… The Neuroscience of intermittent fasting and how, from an evolutionary perspective, our brains evolved to experience metabolic switches- which may offer neuroprotective and cognitive benefits.

@drsanil.bsky.social and @realjesseluke.bsky.social, this happened soon after I fell asleep and I suspect was the combo of low-level clonidine from a much earlier dose, lemborexant, and the elevated/stimulated state empagliflozin puts me in. A state that the lemborexant brings to an end after 3 days

🎥New Video Release on Psychiatry Simplified: Understanding Anhedonia 🚨 youtu.be/lTvdGFJeAMM

New YT video - Not All SSRIs Are the Same! 🚨 youtu.be/_vITGe0XxuI 👉Receptor profiles & metabolism – Why some SSRIs are activating, others sedating 👉Drug interactions & CYP inhibition 👉Withdrawal risks – What to monitor 👉Patient-tailored selection – Matching SSRI pharmacology to symptom profile

🧵The Stability Paradox in BPD: Why Attention-Seeking Is Not What You Think 🚨 Most misunderstand attention-seeking in BPD. Let's break it down 👇Thread on Twitter X x.com/sanilrege/st...

New Video: NAC in Psychiatry –Evidence, Mechanisms & Clinical Use 🚀 N-acetylcysteine (NAC) is one of the few supplements with a reasonable evidence base across psychiatric disorders, including schizophrenia, depression, OCD, bipolar disorder, and addiction. Video 👉 youtu.be/CfHJGR8NXeE

x.com/sanilrege/st... Great thread on BPD and restricted access to care by @drsanil.bsky.social

Psychedelics and the Free Energy Principle ( FEP) 🍄- Video👇 A while ago, someone asked “explain the Free Energy Principle to a 5-year-old.” Video 👉 youtu.be/CgkGjKKyyf8 Enjoy the ride! 🚀🐛🧠

Is ADHD Overdiagnosed ? A Nuanced Exploration 👇 youtu.be/rdmdpMlmU-Q?...

Coming up tomorrow on The Psychiatry Simplified Channel 🚀 Why is ADHD on the Rise? 🚨 You can subscribe ( or hit the bell icon) to be notified 👇 www.youtube.com/@psychiatrys...

New YT video 🚀🎥👉Why Fentanyl Is More Addictive and Deadly Than You Think youtu.be/9u5AE5Gy-3Y

But what if the disinformation campaign emerges organically, over years, via individual opinions and blogs by those who have respect and credibility among peers? The Antipsychiatry movement is a case in point. #MedSky #PsychSky #MadSky

Immuno-Metabolic Depression: The Overlooked Subtype?🚨 👉 Affects 20-30% of those with depression. ⚠️ Characterised by: 1️⃣ Energy-related symptoms: hypersomnia, fatigue, hyperphagia, anhedonia. 2️⃣ Inflammation: raised CRP, cytokines. 3️⃣ Metabolic issues: obesity, dyslipidaemia, insulin resistance.

ADHD and Anxiety - What’s the Connection 👉 NEW YT video for the Psychiatry Simplified Channel 👉 Understanding ADHD Beyond Hyperactivity and Inattention youtu.be/CYWLhkyjz0M

youtu.be/Zue2cZTkB6k?...

New YT video 🚀🎥 PTSD Treatment: Why Psychotherapy Isn’t Always the First Step Video 👉youtu.be/Zue2cZTkB6k

Genuinely enjoyed this new video by @drsanil.bsky.social discussing treatment approaches for PTSD! Link 👇🏼 youtu.be/Zue2cZTkB6k?...

Embracing complexity ✅ This image shows the non-linear progression from stress to Type 2 Diabetes. In psychiatry, understanding such complexity is essential, as many conditions involve similar interconnected mechanisms affecting brain networks, neuroinflammation, and long-term adaptation.

Monocausotaxophilia - The tendency to explain everything as based on a single cause. (Ernst Pöppel, Neuroscientist) 🚨 The love of single explanations is a key driver of misunderstandings in psychiatry and medicine. Expertise lies in navigating uncertainty and embracing complexity. ✅

“Uncommon presentations of common diseases are more common than common presentations of uncommon diseases.”

1️⃣Mood: transient, low-intensity emotional state without a clear cause. 2️⃣Feeling: The conscious experience of emotions, playing out in the mind. 3️⃣Affect: A foundational state combining internal and external signals,varying in valence. 4️⃣Emotion: Intense, short-lived responses to stimuli.

Predicting Parkinson's Disease : Early Clues That Matter 🚨🚨 Men with constipation, REM sleep behaviour disorder (RBD), and hyposmia have a 23x higher risk of developing Parkinson’s Disease (PD) within 3 years.

New YT Video📹🚀 We are bundles of habits. 🧠 👉Neuroscience of Addiction: From Survival Circuits to ‘Hijacked’ Habits youtu.be/9zclgdSdfBA We are creatures of habit, wired for survival, but the same brain circuits that automate our lives make us all vulnerable to addiction's hijacking!

Every patient encounter is an opportunity to not only treat the present but also prevent future risks, vulnerabilities, and setbacks. Sustainable recovery is about thinking beyond the moment. #MentalHealth #Psychiatry

A systematic review of 113 RCTs on ADHD in adults found stimulants and atomoxetine effective for symptom reduction short-term but with limited impact on quality of life. Non-pharmacological strategies showed inconsistent benefits. www.thelancet.com/journals/lan...

🚨 New Video 🚨 A Clinician’s Guide to Navigating Complex Illness: ME/CFS, POTS, and Long COVID Explained 🎥 1.5 hours of my clinical insights, practical strategies, and a journey through uncertainty. Video:👉 youtu.be/Ej9yyOsGYNg?...

Just published: Brain Insulin Resistance ( BIR) – Mechanisms, Neuropsychiatric Implications & Therapeutic Frontiers Explore how insulin resistance impacts the brain, links to psychiatry, and emerging treatments for BIR 👇 psychscenehub.com/psychinsight...

PCOS is not merely a reproductive condition- it is a systemic disorder with significant neuropsychiatric comorbidities, including depression, anxiety, OCD, and personality disorders. Proactively addressing PCOS can be a disease-modifying intervention. ✅ psychscenehub.com/psychinsight...

Antidepressant Discontinuation and Relapse 🚨 “An increase in amygdala reactivity was associated with risk of relapse after antidepressant discontinuation and may represent a functional neuroimaging marker that could inform clinical decisions around antidepressant discontinuation.”

Evidence Informs, Guidelines Guide, Clinicians Think! 🚀 Sums up today’s 4 hour talk on the Art of Strategic Problem Solving. As clinicians, we must learn patterns across multiple models, disciplines, and concepts to master pattern recognition. The broader the patterns, the sharper the recognition✅

Trauma-Psychotherapy first In PTSD may be reductionistic 🚨 “Despite decades of documentation, it is remiss of the field that the underlying neurobiological dysfunction in patients plays no role in planning the nature of the optimal treatment"[Nijdam et al, 2023] psychscenehub.com/psychinsight...

A sneak peek at tomorrow's The Art of Strategic Problem Solving in Psychiatry 🚀 3-hour journey through psychosis, affective disorders, trauma, OCD, ED, pain… We'll explore first principles, apply tools effectively, and use case studies to challenge the “trial and error” view of psychiatry.