helsenjana.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

helsenjana.bsky.social

Evolutionary cell biology, chromosomes, yeasts, and occasional SciArt🧬🧪🎨. Postdoctoral fellow at the labs of Gautam Dey (EMBL) and Gavin Sherlock (Stanford University).

39 posts 1,404 followers 828 following

Posts 14 Comments 35

It’s out! The evolutionary origins of yeast point centromeres uncovered! “Ancient co-option of LTR retrotransposons as yeast centromeres” www.biorxiv.org/content/10.1...

submitted 37 days ago • 1 comment

📢Excited to share our new paper in Nature Physics @naturephysics.bsky.social: Cooperative hydrodynamics accompany multicellular-like colonial organization in the unicellular Stentor! How do single-celled organisms benefit from teamwork? Let’s dive in! #Multicellularity nature.com/articles/s41...?

submitted 60 days ago • 9 comments

My postdoctoral work on the non-canonical role of an autophagy-related protein at the spindle pole body (SPB) is now out in @plosbiology.org (doi.org/10.1371/jour...).

submitted 60 days ago • 2 comments

Happy to share our paper’s final version on the evolution, structure, and membrane binding / remodeling of Asgard ESCRT-III proteins! And my first 🦋 post! www.science.org/doi/10.1126/...

submitted 114 days ago • 1 comment

Cool paper on evolutionary constraints and trajectories shaping point centromere evolution in budding yeasts by @helsenjana.bsky.social @gautamdey.bsky.social @gsherloc.bsky.social www.biorxiv.org/content/10.1...

submitted 135 days ago • 0 comments

Centromere evolution isn't a sudden switch! Our study shows centromere transitions are a step-by-step process driven by a combination of drift and selection. Discover how the kinetochore interface shapes this gradual change in our new preprint 🥳 doi.org/10.1101/2025.01.16.633479 🧵(1/8)

submitted 135 days ago • 2 comments

Happy holidays from the #DeyLab and 🥂 to a wonderful 2025! (If you haven’t seen one of our cards before, you’re thinking, oh that’s sort of vaguely unsettling, YES! And we are here for it 😊)

submitted 158 days ago • 2 comments

I am excited to share this animation of the budding yeast inner kinetochore. Created for David Barford's lab @mrclmb.bsky.social This DNA-binding protein complex acts as an anchor for the spindles that pull chromosomes apart during mitosis. www.science.org/doi/10.1126/... #blender #animation #b3d

submitted 188 days ago • 7 comments

Seeing this community grow and thrive is so exciting and frankly inspiring. Here's my artsy take on the current #SciSky vibes ✨☁️

submitted 194 days ago • 0 comments

Haven't seen a yeast pack yet, so I made one! Help the yeast people flocculate, share, and send me your name if you like to be added. go.bsky.app/PyUwqLU

submitted 223 days ago • 3 comments

I put together a list of profiles in somehow related subjects of chromosome biology go.bsky.app/KqsM3kd

submitted 201 days ago • 3 comments

New preprint! #UExM for >200 microbial eukaryotes, all 1670 volumes available via FIJI/Mobie! Thank you to everyone that made it possible especially Armando and @hiralshah.bsky.social , @gautamdey.bsky.social @centriolelab.bsky.social, and @dudinlab.bsky.social! tinyurl.com/PlanExM1

submitted 226 days ago • 1 comment

How do karyotypes evolve? Turns out an intracellular tug of war within the metaphase spindle sets the limits for chromosome number evolution. Excited to see our study out today in Nature Cell Biology doi.org/10.1038/s41556-024-01485-w 1/9

submitted 297 days ago • 3 comments

Ever wondered how the mitotic machinery can tolerate large changes in chromosome number? In my first postdoc preprint with @gautamdey.bsky.social @gsherloc.bsky.social & Hashim Reza, we show that spindle architecture is a constraining factor for karyotype evolution doi.org/10.1101/2023.10.25.563899

submitted 585 days ago • 2 comments