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igorulitsky.bsky.social
Associate Professor, Weizmann Institute of Science. RNA biologist, interested in what (long) RNA molecules do and how. Father of 4.
180 posts 2,481 followers 848 following
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Posts 24 Comments 26

"i didnt follow the recipe and it tastes like shit. 2 stars"

submitted 2 days ago • 138 comments

Stop the doom scrolling! A new 🗞️ from my lab, describing one of our flagship projects of many years we are super excited to share: "Inducible formation of fusion transcripts upregulates haploinsufficient CHD2 gene expression". A 🧵 biorxiv.org/content/earl...

submitted 7 days ago • 4 comments

Super cool work on the function of intrinsically disordered regions in regulating transcription factor DNA binding.

submitted 8 days ago • 1 comment

How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

submitted 9 days ago • 6 comments

It was a pleasure to write a N&Vs on @danielibrahim.bsky.social's latest paper in @natgenet.nature.com. Enhancers tend to stay put even if their sequence changes beyond recognition. Quoting Il Gattopardo, everything must change so that everything can stay the same: www.nature.com/articles/s41...

submitted 9 days ago • 4 comments

A 🧵 to walk those interested through this paper...

submitted 20 days ago • 5 comments

Online now at @cp-cell.bsky.social , the culmination of a 12-year effort. 🧵 to follow later this evening www.cell.com/cell/fulltex...

submitted 20 days ago • 1 comment

And, again, WHERE IS #BIGPHARMA in defending #basicscience? laying low? playing dead? Waiting it out? Do SOMETHING! SPEAK UP! Use your gigantic lobbying machine to defend us instead of peddling your wares and increasing your profits. Or do you think highly trained workforce grows on trees?

submitted 34 days ago • 6 comments

Perhaps the best computing advice there is - learn to use Ctrl-R in UNIX

submitted 44 days ago • 0 comments

Somehow, one here less talk about "overlay journals" now that every posted preprint results in 200 different spam e-mails within a week

submitted 44 days ago • 0 comments

The great thing about fighting back against this stuff is that if you end up losing anyway you get the same outcome you’d have gotten from complying but you don’t have to fucking hate yourself too.

submitted 52 days ago • 53 comments

I highly recommend this inspiring new book by Nahum Ulanovsky! A plea for neuroscientists to embrace “Natural Neuroscience”: use emerging technologies to uncover meaningful behavior and neural representations in free-roaming animals exposed to real-world stimuli. mitpress.mit.edu/978026204499...

submitted 51 days ago • 3 comments

www.nature.com/articles/s41... #spatialbiology #RNAbiology

submitted 54 days ago • 2 comments

The Daily with Chris Rufo today is the scariest shit I've heard in a while. A must-listen for any academic worldwide. The previous episode with the president of Princeton is also excellent, but less insightful. open.spotify.com/episode/5mnY...

submitted 55 days ago • 0 comments

🚨I could not be more excited to share our new preprint on saturation genome editing of the small nuclear RNA (snRNA) RNU4-2: www.medrxiv.org/content/10.1... A super fun collaboration with incredible duo @gregfindlay.bsky.social @joachimdejonghe.bsky.social from @crick.ac.uk 🧬🖥️🩺 🧵1/12

submitted 55 days ago • 4 comments

"I really think we all need to be speaking up right now. . . . I think this would be so much stronger if many more of my fellow presidents were speaking up." - Chris Eisgruber www.nytimes.com/2025/04/09/p...?

submitted 56 days ago • 32 comments

New preprint 📜 from @AlanMonziani in the lab – EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology www.biorxiv.org/content/10.1... . A🧵

submitted 57 days ago • 2 comments

submitted 58 days ago • 23 comments

This is high art

submitted 60 days ago • 545 comments

Last Saturday morning ☕ saved for this gem: www.science.org/doi/10.1126/... CRISPR screening reveals TRIM25 as a pH-sensitive sensor that specifically targets foreign RNAs entering through endosomes. N1-methylpseudouridine helps repel TRIM25 binding & enhances protein production.

submitted 61 days ago • 2 comments

What was that you said? You are looking for new #RNA research to read in the weekend? You are in luck! 📣 📣 Check out the new preprint from our lab!!!! 📣 📣 www.biorxiv.org/content/10.1...

submitted 62 days ago • 3 comments

It's difficult to focus on science with everything going on, but I still enjoy hearing about other people's work here, so I want to continue sharing ours. Congrats to postdoc Jong-Sun Lee for his outstanding work published in @cp-molcell.bsky.social! Details in thread👇 www.cell.com/molecular-ce...

submitted 63 days ago • 4 comments

I'm happy to share our work on the neurodevelopmental impact of ADNP mutations in ASD and beyond. It has been an exciting ride to share with @alessandrovitriolo.bsky.social, Mariana, and the people of the Testa and Poot Labs. Full paper here: www.biorxiv.org/content/10.1... Thread below 🧵

submitted 63 days ago • 1 comment

Don't think I've ever met scientists as terrified/depressed as I've seen in the US this week (and I live in a war zone).

submitted 64 days ago • 2 comments