isabelmeister.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO

submitted 14 days ago • 9 comments

Lipidomics combined with CRISPR can help decipher the complex biochemistry that allow cancer cells to evade elimination. www.nature.com/articles/s41... #Nature fruitful collaboration with @JavierGarcia-Bermudez UT Southwestern #VitaminE

submitted 1 day ago • 0 comments

Call from 6 Swiss Fields Medal laureates to preserve science funding science-under-threat.com

submitted 9 hours ago • 1 comment

Participated in the MetabolomeXchange stakeholder meeting, one day before #metabolomics2025. So many valuable discussions!

submitted 3 days ago • 0 comments

This is a great article by @joachimgoedhart.bsky.social on @dev-journal.bsky.social about color choice in #DataViz, thenode.biologists.com/data-visuali..., also check out his super useful #DataViz tools at huygens.science.uva.nl 🧪🧬💻

submitted 4 days ago • 5 comments

I gave in! After students asking for it, I now made a simple figure design checklist. To help all scientists w/o graphic skills create clear, accessible, and truthful charts! -> Out in @nature Cell Biology: rdcu.be/erwl4 #DataVisualization #PhD #SciComm Thx for review @bethcimini.bsky.social + 2

submitted 6 days ago • 11 comments

www.nature.com/articles/s41...

submitted 7 days ago • 0 comments

Out today, we report how small chemical modifications in the metabolism of ergosterol are needed for yeast membranes to phase seperate into ordered yet fluid domains www.science.org/doi/10.1126/... (1/n)

submitted 61 days ago • 4 comments

"Apart from hydrogen, the most common thing in the universe is stupidity." -- Harlan Ellison.

submitted 7 days ago • 1 comment

New preprint alert! 🚨 We compared metabolite coverage of three blood microsampling devices as an alternative to conventional samples for human biomonitoring. All devices were suitable for #metabolomics analysis and the choice of device depends on the application chemrxiv.org/engage/chemr...

submitted 8 days ago • 1 comment

📆 6 days until we meet in Prague for #Metabolomics2025! Have you checked out the program and planned your sessions? Full session schedule available here: 👉https://tinyurl.com/y6tk3a99 #EMN #ConferenceCountdown #Prague2025

submitted 8 days ago • 0 comments

#neuroskyence who knew… If mom is on high fructose diet, neuro development and microglia phagocytosis in progeny is impaired

submitted 10 days ago • 1 comment

[THREAD] Petit coup de gueule contre les états et les pays qui sont ceux que je connais par rapport à la science et au partage de la connaissance et des informations scientifiques. Je sais pas vers où je vais avec cette réflexion mais je suis très agacé. Surtout après 5 ans de Covid.

submitted 11 days ago • 2 comments

Preparing for my first #metabolomics2025. Fantastic program with workshops, oral presentations and posters. Also happy to meet #bluesky friends, some for the first time in-person. Our poster number 1207 is on air - about environmental #cyanobacteria analysis. #teammassspec www.metabolomics2025.org

submitted 10 days ago • 0 comments

Ancient DNA from 6,000yo hunter-gatherers in Colombia reveals a lost genetic lineage. They were part of the earliest wave into South America, but left no trace in today’s populations. #Archeology #SouthAmerica #biology 🧪⚒️🧬 AP link apnews.com/article/hunt... Paper www.science.org/doi/10.1126/...

submitted 13 days ago • 2 comments

Joining the race to the bottom has never been cooler... www.biorxiv.org/node/4580343... www.biorxiv.org/content/10.1...

submitted 30 days ago • 0 comments

Scientists built a fast new system to grow human microglia, the brain’s immune cells, from stem cells in just four days. This could speed up research on brain disease and immunity. #bio #Neuroscience #StemCells #Microglia 🧬🧪🧠 Paper www.nature.com/articles/s41...

submitted 14 days ago • 0 comments

This is such an incredible paper. Must read if you care about metabolites and cores organ interactions. For me most interesting finding is that the liver is NOT the only organ that converts cholesterol to bile acids. But ther are so many cool onserbwtions www.cell.com/cell/abstrac...

submitted 12 days ago • 0 comments

D-1 before the 17th JS of @rfmfmetabolomics.bsky.social in Paris! Always a pleasure to reconnect with fellow metabolomists. Excited for what’s to come!

submitted 14 days ago • 0 comments

By deep characterisation of 186 N-glycan standards, we @thencfg.bsky.social have made the most comprehensive targeted LC-MS glycomic assay to date. Non-reduced native glycan analysis is key. We hope this enables anyone with QqQ and interest in #glycotime to measure specific N-glycan structures.

submitted 14 days ago • 4 comments

I've been asked about my slides on the #ZenoTOF8600. We uploaded the poster, which includes the data and comments, plus all key data and results at polybox.ethz.ch/index.php/s/.... Feel free to reshare or to ping me for more.

submitted 21 days ago • 0 comments

New Preprint ... This was a bit different of a project than what we normally do for hardware comparisons. I think there is a lot of potential in the methods mentioned here for calibrating the instrument response to a common scale. Nice work by @chrhsu.bsky.social! www.biorxiv.org/content/10.1...

submitted 23 days ago • 4 comments

I am really pleased we managed to squeeze this story out during #ASMS2025. This is our contribution relating to the fantastic Omnitrap/Orbitrap. What we thought would be a straightforward conversation of our exploris-omnitrap turned into quite a journey. (1/n) www.biorxiv.org/cgi/content/...

submitted 23 days ago • 1 comment

A flexible end-to-end automated sample preparation workflow enables reproducible large-scale bottom-up proteomics https://www.biorxiv.org/content/10.1101/2025.05.23.655690v1

submitted 27 days ago • 0 comments

Our latest preprint on peroxisomal fatty-acid transport is live!! @ohsunews.bsky.social #OHSU @uofcalifornia.bsky.social #UCSF

submitted 28 days ago • 1 comment

Feel like you’re stuck in an endless postdoc? I can relate! I bet you do not beat my record… even then I did manage to find my dream PI position. Thanks to @the-node.bsky.social for the interview on my unusual career path.

submitted 32 days ago • 1 comment

New paper from our lab! In this study, we show that AML cells critically depend on LDHA to maintain their NAD+/NADH balance. Congrats to first author Ayşegül Erdem and all co-authors! cancerandmetabolism.biomedcentral.com/articles/10....

submitted 36 days ago • 2 comments

Very happy to see this finally published in PNAS: "Myelin sheaths can act as compact temporary oxygen storage units as modeled by an electrical RC circuit model", www.pnas.org/doi/10.1073/pnas.2422437122

submitted 36 days ago • 0 comments

Excited to collaborate with Caroline Alexander’s group and @lamminglab.bsky.social demonstrating the contribution of dietary lipids to skin lipids and their insulating properties. Proud of Raghav for leading this collaboration in my lab! @natcomms.nature.com www.nature.com/articles/s41...

submitted 39 days ago • 1 comment

ICYMI:

submitted 46 days ago • 0 comments

Information into how @europepmc.org works..how similar it is to Pubmed and PMC..and more..

submitted 40 days ago • 0 comments

If there any #Sciex decision makers here on Bluesky - I urge you to reconsider. Skyline/Proteowizard support is not only important for your customers using these tools, but it also benefits other bioinformatics efforts that depend on these tools.

submitted 41 days ago • 0 comments

🥳🤩Thrilled to share that our paper is officially published in Reproduction! Our study, "Towards a kingdom of reproductive life - the core sperm proteome," integrates cross-species proteomic data from 12 vertebrates, revealing fundamental insights into sperm biology and fertility 👉 lnkd.in/e-4eYqwK

submitted 41 days ago • 2 comments

Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested. 1/n

submitted 41 days ago • 15 comments

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

submitted 42 days ago • 34 comments

Disappointing to see, across both parties. Sciex is no longer providing funding for Skyline/Proteowizard as part of the multi-vendor agreement to keep Skyline supported across all major vendors. I can see the arguments from both sides, just a shame it's resulted in this.

submitted 42 days ago • 6 comments

Postdoctoral position in Computational Biology open! Our Lab is trying to understand how human T cell immunity is regulated across the human body as part of the ERC CoG funded project ORGANise-T. More info 👇 zielinskilab.com

submitted 43 days ago • 1 comment

📢 We have an open PhD position in our group! Come to Geneva🇨🇭 to develop new methodological approaches in LC-MS metabolomics for human toxicology, while enjoying the great Swiss outdoors & chocolate 🏔️🍫 jobs.unige.ch/www/wd_porta... 🧬🧫🧪🖥️ #metabolomics #lipidomics #teammassspec #MassSpecRSS #chemsky

submitted 45 days ago • 1 comment

Our latest manuscript describes an #LCMS platform profiling Phase II metabolites. We annotated 424 mercapturates, glucuronides, sulfates linked to over 200 environmental chemicals. This demonstrates ILGA's value for advancing #Exposomics Link doi.org/10.1016/j.en... #MassSpectrometry #Metabolomics

submitted 47 days ago • 0 comments

Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...

submitted 49 days ago • 6 comments

Proud present our latest work led by Blessy Paul, now in Developmental Cell @cellpress.bsky.social. Here, we characterize an ER-localized antioxidant enzyme in humans and Drosophila that acts as a lipid quality control factor to suppress ER lipid oxidation. www.cell.com/developmenta...

submitted 50 days ago • 0 comments

I'm thrilled to be co-organizing the very first EMBO Workshop bridging mitochondria and brain research - a powerhouse of science, ideas, and amazing speakers! 🧠🔬 📅 registration closes MAY 30th, so don’t wait to snag your spot! Stay tuned - more updates about the topics and speakers coming soon! 🎙️

submitted 50 days ago • 1 comment

☕Kim et al. show that NAD+ kinase 2 serves as a source of mitochondrial #NADPH to support #mitochondria fatty acid synthesis, protein lipoylation and mitochondrial oxidative #metabolism. rdcu.be/ekymW bit.ly/3GC89sm

submitted 52 days ago • 0 comments