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jeromeebb.bsky.social
🧬 Human Genetics scientist | computational biologist | foodie | coffee snob ☕️ |🖖🏽🔬👨🏾‍💻🏳️‍🌈| all opinions here are my own 🐒
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Just commented here too - can be anonymous, and standing up for NSF/NIH takes less time than standing in line at the grocery store checkout!!

Was happy to provide a little excerpt, along with others, about the recent @hhmi.org Hanna Grey decision last week as an applicant and a former Gilliam Fellow that knows how important these fellowships are for early career scientists with limited resources.

Let's talk about these two department store owners: brother and sister Louis Bamberger and Caroline Bamberger Fuld. From Newark, New Jersey. They are random people, basically. But in the late 1920s, with fascism taking over Europe, they made a choice that profoundly changed the world: 🧵

What cutting science and biomedical grants mean for the nation... www.npr.org/2025/04/25/n...

open.substack.com/pub/paulkrug...

Number of genetic differences between random pairs of African individuals (black points) and a corresponding random European (blue points). 20 random samples. One instance: a person from Russia has fewer differences to a Kenyan than that same Kenyan to a Namibian.

This is Arang and Aro. Aro is giving them the ol' razzle dazzle, and Arang is giving nothing at all. 12/10

RFK Jr. is ending the federal Narcan distribution program credited with the recent steep decline in overdose deaths. This despite his own past heroin addiction and his own brother dying of a drug overdose in 1984.

These sea turtles dance for joy when they magnetically sense it’s snack time. Learn more on #InternationalDanceDay: scim.ag/42VqsSz

Cue “When the Fats Come Marching In” (I will let myself out)

“Science is a smart, low cost investment. The costs of not investing in it are higher than the risk of doing so… talk to people about science.” - @kevinochsner.bsky.social makes his case to the field #sans2025

“If left unchallenged, a rising wave of white nationalism in many parts of the globe could threaten the progress that has been made in science — and broader society — towards a more equitable world,” writes Genevieve Wojcik in a Comment article for Nature. 🧬 🧪

Delighted to see our work on #diatom motility published in @pnas.org !🎉 doi.org/10.1073/pnas... These abundant single-celled algae are responsible for a significant portion of the air we breathe yet often overlooked. Here we show how how diatom (raphe) shape impacts their gliding function... 1/3

Intensive blood pressure reduction is effective in lowering the risk of all-cause dementia in patients with hypertension @naturemedicine.bsky.social www.nature.com/articles/s41...

You can't report on this garbage without informing readers of the literal identical policy under Hitler. www.nytimes.com/2025/04/21/u...

genomebiology.biomedcentral.com/articles/10.... Quite an indictment of some of the current single cell "virtual cell" foundation models. Even for the relatively mundane applications, cell labeling, batch correction etc, they are poor compared to much simpler & cheaper methods.

In today's episode of the Night Science Podcast we talk with Martin Schwartz from Yale about the importance of stupidity in science: while learning science makes you feel smart, true scientific discovery often involves feeling stupid, because it means venturing into the unknown.

This is absolutely fking insane. We're going to be in for a rough ride. Let's buckle up, hold strong & support each other as much as possible.

New preprint out! This is probably my most important paper. To my deep chagrin, it has no math. XIST is a non-coding RNA exclusive to XX females. It silences one of the X chromosomes. So what is it doing in male heart Schwann cells?

ICYMI: A biorefrigerator for vaccine cold storage in energy-scarce regions

New paper out in Genome Biology! 🎉 We lay out best-practice guidelines for releasing variant effect predictors, developed through the Atlas of Variant Effects Alliance @varianteffect.bsky.social Open, interpretable, and clinically useful VEPs are the goal. 📄 doi.org/10.1186/s130...

With Butovsky Lab, we show that silencing TIM-3 in brain-resident immune cells prevents neurodegeneration in a mouse model of #Alzheimer’s disease. Deletion of TIM-3 in microglia enhance phagocytic clearance of toxic amyloid beta. #Immunosky🧪 www.nature.com/articles/s41...

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

High-throughput proteomics is helping us understand the biological basis (with causality) for diseases. Today for asthma www.cell.com/cell-genomic... @markmccarthy985.bsky.social

🧬 February's most-read Genetics paper looks at how #RNA travels between cells to control genes across generations #epigenetics: elifesciences.org/articles/991...

Researchers discover a rare example of defensive mimicry in birds. scim.ag/42407j7

1. For the past thirty years I've had the best job in the world. 
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.

Hearing about some US universities advising their international scientists (green card holders & visa holders) not to leave the US for the time being for fear that re-entry will be non-trivial even with all the necessary documents in hand. Is this happening at your institution?

University of California announced a systemwide hiring freeze. This affects not 1 but 10 campuses (including UCLA, UC Berkeley, UC San Francisco, UC San Diego among others) plus 3 national labs with impact on medical and scientific research and local economies. www.reuters.com/world/us/uni...

Eric Green is out as head of National Human Genome Research Institute www.statnews.com/2025/03/17/t...

This is sad not just for genomics in the US, but across the world: Eric has been an incredibly effective global champion for the power of genomics and the impact of genomic medicine.

Scientists have revealed why not all individuals with a high inherited risk of glaucoma may ultimately develop the disease. buff.ly/kdDuO9n

How does SARS-CoV-2 lead to the multisystem inflammatory syndrome in children, a rare, potentially fatal condition? www.nature.com/articles/s41... High levels of TGFβ interfere with the child's response to control Epstein Barr virus, leading to its reactivation and severe inflammation @nature.com

Awesome day in Salem 😍 #standupforscience #researchmatters #sciencematters #factsmatter 💚

Grateful to be able to take today off to participate in the #Boston #StandUpForScience rally! 🧵

Good God. The biggest chunk of this is $3 million to determine why women suffer more from asthma than men. They're giving estrogen to male mice to see if that's the culprit. WH describes this as research on "transgender mice". Clearly someone in the Administration can read; they hope you can't.

@carolynbertozzi.bskyverified.social I can’t see you with the thousands of people in front of me, but I love hearing your words. #standupforscience