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jojolab.bsky.social
Japan based neuroscientist, Team Leader at RIKEN Center for Brain Science, studying the neural basis of emotional learning & memory, adventure cyclist
26 posts 401 followers 431 following
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Noradrenaline and microglia maintain plasticity-rigidity balance to safeguard rapid emotional learning in the prefrontal cortex https://www.biorxiv.org/content/10.1101/2025.06.16.659241v1

submitted 1 day ago • 0 comments

Our work with Pablo Tano, @hyunggoo-kim.bsky.social Athar Malik, Alexandre Pouget and @naoshigeuchida.bsky.social exploring how dopamine neurons could enable multi-timescale reinforcement learning in the brain is out in @nature.com www.nature.com/articles/s41...

submitted 14 days ago • 8 comments

Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...

submitted 20 days ago • 4 comments

📣 #SfN25 abstract submission is now open! Share your research with the global neuroscience community. Start now to avoid the last-minute rush! 🔗 bit.ly/3G5vEde #NeuroSky #AcademicChatter

submitted 29 days ago • 0 comments

Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested. 1/n

submitted 35 days ago • 15 comments

I’m excited to share a new paper from the lab. The study led by Xiaowei Gu reveals how the mPFC encodes complex emotional memories, using an internal model to infer emotional associations and memories via projections to the amygdala. a🧵(1/8) rdcu.be/el19t

submitted 35 days ago • 10 comments

Our paper is out in Nature. By examining various inputs to the motor cortex during learning, we found that thalamic inputs learn to activate the cortical neurons encoding the movement being learned. Tour de force by Assaf in collab with Felix and Marcus. Congrats! www.nature.com/articles/s41...

submitted 42 days ago • 3 comments

Pleased to share the final published version of @glopez.bsky.social's work in @currentbiology.bsky.social! www.sciencedirect.com/science/arti... "Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning" Congrats, Gaby!!!

submitted 57 days ago • 6 comments

Our new paper is out in Science. What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons. Congrats Jake! www.science.org/doi/10.1126/...

submitted 62 days ago • 2 comments

Thanks to all who contributed to the special issue of Cerebral Cortex honoring my career academic.oup.com/cercor/issue...

submitted 65 days ago • 0 comments

How do we associate the flavors we experience during a meal 🍽️😋 with postingestive effects like food poisoning 🤢🤮 that arise much later? Our answer in @nature.com this week: Illness signals from the gut reactivate and strengthen flavor representations in the amygdala. 📄: nature.com/articles/s41...

submitted 76 days ago • 10 comments

Our new paper. Prospective contingency explains behavior and dopamine signals during associative learning. Collaboration with @neurovenki.bsky.social , @gershbrain.bsky.social rdcu.be/ed1na

submitted 93 days ago • 0 comments

www.sciencedirect.com/science/arti... "Advances in neurotechnologies... are transforming neuroscience... A recent meeting highlighted the resulting challenges in global collaboration ... emphasizing the need for ... diagnosing and treating brain disorders." - co-authored by yours truly 🧠📈 🧠💻

submitted 100 days ago • 2 comments

Check out a new lab paper from Mayumi Watanabe's thesis work showing how different subregions of medial prefrontal cortex differentially regulate extinction of aversive memories through projections to the locus-coeruleus-noradrenaline system: doi.org/10.1038/s413...

submitted 103 days ago • 3 comments

The first paper from Akira Uematsu's lab (first author @moon240.bsky.social)!: molecularbrain.biomedcentral.com/articles/10.... And check out his lab website: www.uematsu-lab.com/research/

submitted 104 days ago • 0 comments

Groundbreaking work by Dr. Soohyun Lee from the National Institute of Mental Health at NIH The brilliant young scientist faces termination. Science like this leads to discoveries that can revolutionize how we understand the brain. doi.org/10.1038/s415... #neuroscience #neuroskyence

submitted 104 days ago • 2 comments

Calling all amygdaloids!!! The #AmygdalaGRC is coming up this summer in Barcelona. We’ve got talks, posters, networking, power hour, and tons of fun planned. 👀 the program 👇🏻 We’re accepting folks on a rolling basis, apply soon to make sure you get a spot: www.grc.org/amygdala-fun...

submitted 106 days ago • 0 comments

🚨📃New Wassum Lab Paper📃🚨 Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇 www.nature.com/articles/s41... Free full text: rdcu.be/eaxEv

submitted 119 days ago • 27 comments

Japan can be a science heavyweight once more — if it rethinks funding Research leaders call for an end to substantial underfunding of interdisciplinary research in Japan. On my current visit to 🇯🇵 I can see the country is ready for a change #japan #academicSky 🧪 www.nature.com/articles/d41...

submitted 127 days ago • 0 comments

We are happy to have contributed to this exciting paper from Yoshi Saito and Masa Murayama on a distributed circuit mechanism for emotional enhancement of perceptual memory www.cell.com/neuron/fullt...

submitted 140 days ago • 0 comments

An interesting review proposing a model in which amygdala intercalated cells form a key system for integrating divergent inputs and orchestrating brain-wide circuits to generate behavioral states attuned to current environmental circumstances and internal needs. www.nature.com/articles/s41...

submitted 185 days ago • 0 comments

I'm struck by how grad students in psych and neuro programs aren't generally expected to know basic facts about animal learning. For the psychologists, it has an odor of behaviorism, and for the neuroscientists it has an odor of psychology. Yet it's so fundamental (in my view).

submitted 187 days ago • 9 comments

Check out our pre-print from Xiaowei Gu! It shows how the medial prefrontal cortex encodes an internal model of emotional associations which can be used for inference biorxiv.org/content/10.1...

submitted 193 days ago • 0 comments

Excited to share our new paper out now @natureportfolio.bsky.social, where we identified neural signatures of stress susceptibility and resilience in the amygdala-ventral hippocampal network to enable control of anhedonia! <https://www.nature.com/articles/s41586-024-08241-y> Thread below:

submitted 196 days ago • 2 comments