jonnyfinlay.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

submitted 39 days ago • 0 comments

So has anyone put a really, truly, AI-from-scratch antibody into the clinic yet? Press releases aside, the answer is “absolutely not”.

submitted 133 days ago • 7 comments

endpts.com/with-first-d...

submitted 141 days ago • 0 comments

Twittler deleted off phone. Feels good TBH.

submitted 149 days ago • 0 comments

submitted 152 days ago • 1 comment

Would just like to also stress that I think diversity initiatives themselves are also inherently good for robustness and social harmony.

submitted 154 days ago • 0 comments

A superb example of why this kind of ‘purge’ is asinine. What pharma company would NOT like to be able to maximise their understanding of how different genotypes/ethnicities respond to their drug?

submitted 154 days ago • 1 comment

@wendystitch.bsky.social

submitted 157 days ago • 1 comment

submitted 158 days ago • 0 comments

It’s also weird cause why are a bunch of nerds talking about masculine energy? This is software you’re building, not storming Normandy.

submitted 165 days ago • 14 comments

To all who celebrate

submitted 183 days ago • 0 comments

New: A $140M round for Ottimo Pharma, led by former Seagen CEO David Epstein, is the latest example of a surge of investments in a drug class many now believe have the potential to supplant standard-of-care cancer immunotherapies. #biosky www.biopharmadive.com/news/ottimo-...

submitted 189 days ago • 0 comments

An inspiring and exciting day for all of us at OttimoPharma.com Time to accelerate! www.ft.com/content/42c6...

submitted 189 days ago • 0 comments

Several very interesting points www.ft.com/content/a757...

submitted 204 days ago • 0 comments

If you would like to read more about how this affects antibodies, and their preclinical/clinical development, a review of ours here: www.tandfonline.com/doi/full/10....

submitted 205 days ago • 0 comments

Amazing that this even needs to be said. The specificity of antibody binding can be wrecked by the inclusion of a couple more hydrophobic or charged residues in the CDRs. Sticking big greasy fluorophores on proteins inherently changes their chemistry…..

submitted 205 days ago • 1 comment

Strongly recommended.

submitted 213 days ago • 1 comment

Glorious

submitted 214 days ago • 0 comments

The idea of human life moving to Mars is asinine. Preposterous. Childish. Nonsense.

submitted 215 days ago • 1 comment

Reading, as one does, the Wikipedia page on kakistocracy ('government run by the worst, least qualified, or most unscrupulous citizens') and you realise it's not a new phenomenon. This from 150 years ago.

submitted 218 days ago • 3 comments

Oh lord. I have been that soldier. 😆

submitted 219 days ago • 0 comments

Reminded of a classic observation today: if, very quickly, you follow many more people than follow you, you are not famous 😆

submitted 220 days ago • 1 comment

Funny how, for the cab drivers of Northern Ireland, their card readers are ALWAYS BROKEN. Someone should have a word with the manufacturers. The tech is clearly not robust 😏