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katholt.bsky.social
Scientist… pathogen genomics & antimicrobial resistance, computational biology & infectious disease epidemiology. Co-Director LSHTM AMR Centre @lshtmamrcentre.bsky.social holtlab.net | klebnet.org | typhoidgenomics.org | amr.lshtm.ac.uk
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🦠 How do social inequities shape the global AMR crisis? Join us for this seminar exploring the human impact of antimicrobial resistance through ethnographic insights and integrated research approaches. 📅 17 June ⏰ 13:00 BST 📍 LSHTM 🔗 bit.ly/43PDdhr

I appreciate the offers from other scientists to help Harvard (students, labs, etc) through this attack, but what would be most helpful is for you to use your position to contact your elected representatives and make it clear this fight isn't just Harvard, it will affect you, and their districts too

You might be wondering why we haven't updated outbreak.info for months. Well, the reason is that GISAID cut our access in January - as they did others. Without telling us. After a ♾️ back and forth, that is now permanent. More on that soon - and why GISAID should not be trusted with critical data.

NEW research published in PLOS Global Public Health by Delaram Akhavein, @merusheel.bsky.social and @seyeabimbola.bsky.social How health securitisation shapes health system priorities: A realist synthesis journals.plos.org/globalpublic...

Quote Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world. Science is the highest personification of the nation because that nation will remain the first which carries the furthest the works of thought and intelligence. Louis Pasteur

⌛ABSTRACTS SUBMISSION DEADLINE SOON Don't miss your chance to be part of the 6th ESCMID Conference on #Vaccines! ⏰Apply by this Sunday, 01 June 💡More info and how to submit: ow.ly/RBHJ50VQYMH #IDSky #MedSky #clinmicro

Our new paper on the global epi of IMP carbapenemases. We originally called this paper: ‘Planet of the IMPs’ as IMPs are now everywhere. We found IMP variant-specific distributions across species, plasmids, mobile elements and geography www.medrxiv.org/content/10.1... #amr #amrsky #IDsky

Want to boost your understanding of #epidemiology & #InfectiousDisease modelling? Join our course in collaboration with @ukhsa.bsky.social & gain experience of setting up models to monitor outbreaks & transmission. Runs 16 - 27 June 2025 ✍️Apply by 25 May 2025

Myself and @yekwah.bsky.social are running our bacterial AMR databases and genotype prediction course again with @eventswcs.bsky.social. Completely free and study at your own pace. Check out the course objectives below and sign up before June 9th to join us! www.futurelearn.com/courses/anti...

Last week we welcomed over 600 attendees to #ABPHM25! Congratulations to Idowu Olawoye, ‪@westernu.bsky.social‬, for winning the Best Talk prize.🥇 Congratulations also to our joint Poster Prize winners: Farron Brooke, @Stellenbosch University, and Francesca McDonagh, University of Galway. 👏

Next up in our lecture series: Professor Laura Shallcross from @ucl.ac.uk dives into: 👉 Different patient groups that access primary care, secondary care & care homes 👉 Examples of priority drivers of AMR 👉 Why different approaches to tackling AMR are required www.youtube.com/watch?v=Fv6v...

New preprint: we used k-mer matching with suffix match length information to create an assembly-to-assembly alignment algorithm + software, kbo. We wanted to create a reference-based aligner and variant caller that scales to at least 10-100k bacterial queries. www.biorxiv.org/content/10.1...

There's nothing holy about writing discrimination into the law.

Azithromycin can no longer be used for acne, stomach ulcers, or asthma prevention per EMA’s new recommendation. A key move against #antimicrobialresistance. Details 👉 www.ema.europa.eu/en/news/chan...

Aeromonas: Genomic Insights into an Environmental Pathogen and Reservoir of Antimicrobial Resistance https://www.biorxiv.org/content/10.1101/2025.05.22.655522v1

Commensal to pathogen switch in Streptococcus pneumoniae is governed by a thermosensing master regulator https://www.biorxiv.org/content/10.1101/2025.05.23.655729v1

📢Today Pathoplexus announces the inclusion of 2 new viral pathogens: RSV (A & B) and HMPV. These respiratory viruses cause a serious health burden, particularly in infants & the vulnerable, & Pathoplexus aims to support sequence sharing to improve understanding & response. 1/4

Interesting takedown of Colossal Biosciences of 'dire wolf de-extinction' (spoiler: they did not) fame. forbetterscience.com/2025/05/21/c...

Excited to share 9 fully funded PhD projects with NIHR HPRU Public Health genomics at UKHSA and University of Birmingham. Deadline 31 July www.birmingham.ac.uk/research/cen... Ranging from methods development, microbiome, metagenomics and species specific (TB, Strep pneumo, measles) projects

Our "goal is to create a stable, independent non-profit organization that ensures [bioRxiv & medRxiv] remain open...governed by and for the research community, not a single funder...or any one stakeholder." Some common questions about openRxiv answered: openrxiv.org/qa-governanc...

A not very happy Friday. CERI had 6 NIH grants canceled, which will impact operations, surveillance and response to epidemics. We are working to try to minimize disturbance but not easy with 6 grants terminated at the same moment. A crisis is unfolding in SA www.news24.com/southafrica/...

Happy to see this out - please try my code and break it! Also come see me at #ABPHM25 in the showcase today, where I’m presenting AMRGen, an R package for combining and exploring AMR geno pheno data. It was used to help make many of these rules interpretamr.github.io/AMRgen/

Oops messed up the hashtag! #ABPHM25

Excited to share the first beta release of AMRrules at #ABPHM! (Poster 42 tonight) interpretamr.github.io/AMRrules

Late breaker abstracts for IMMEM conference, to be held in beautiful Portugal this September, close Friday May 23! Something for the #ABPHM25 crowd to ponder 🤔 www.escmid.org/congress-eve...

Super talk from @efosternyarko.bsky.social @lshtmamrcentre.bsky.social on nanopore based sequencing of cholera across Africa, with PulseNet Africa partners #ABPHM25 www.biorxiv.org/content/10.1...

It all begins for #ABPHM2025 with keynote from Johanna Hanefeld (RKI).

Welcome to #ABPHM25

We are pleased to launch the KlebNET Genomic Epidemiology Consortium! We aim to build a public metadata repository; systematic risk framework for global genomic surveillance; and genomic epi reviews for high-impact #Klebsiella clones. Join us here: klebnet.org/klebnet-gsp-... #ABPHM25

Delighted to see this paper from danderson123.bsky.social 's PhD out. We have been building tools for AMR gene detection for over a decade now, but multicopy genes remain challenging. Dan shows that with a gene-space de Bruijn graph and long reads, you can do well www.biorxiv.org/content/10.1...

Ooh! Just in time for #ABPHM25? Looks super cool @zaminiqbal.bsky.social @rrwick.bsky.social

Amira: gene-space de Bruijn graphs to improve the detection of AMR genes from bacterial long reads https://www.biorxiv.org/content/10.1101/2025.05.16.654303v1