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kristjanmoore.bsky.social
Research at deCODE genetics: genomic ancestry, ancient DNA, and whatever else needs doing. Trying to have true beliefs. 🇬🇧🇮🇸
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Our paper @hakonjon.bsky.social (missing other colleagues from Bluesky!), Sequence diversity lost in early pregnancy, was published in Nature (@nature.com) today www.nature.com/articles/s41...

submitted 24 days ago • 1 comment

Kári Stefánsson, founder and CEO of deCODE Genetics, the Icelandic company wholly owned by Amgen but operated largely independently, has been fired. www.mbl.is/frettir/innl...

submitted 41 days ago • 2 comments

I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply: recruit.apo.ucla.edu/JPF10275. Please repost!

submitted 47 days ago • 0 comments

Check out our ancient DNA paper on the maritime Punic civilization! 🦴🧬🌊 We find that their Levantine Phoenician cultural ancestors contributed surprisingly little ancestry to Punic sites in the central and western Mediterranean! (1/4) doi.org/10.1038/s415... #aDNA #PopGen #Punic #Phoenician

submitted 52 days ago • 2 comments

I have no idea why this is leading on @theguardian.com website The substance here is 1. Some adults provided written consent for their health data to be shared with researchers for the good of science 2. UK Biobank facilitated this 3. Some researchers are Chinese

submitted 60 days ago • 2 comments

Awesome. I guess obtaining residues for 51 proteins (22 usable for phylogenetics) was important being able to place the sample in a finely resolved proteomic phylogeny: two previous papers (see below) indicate that ~10 protein sequences is insufficient to resolve primates/hominins at species level.

submitted 65 days ago • 1 comment

FRS3 as a BMI-associated gene, encoding an adaptor protein known to act downstream of BDNF and TrkB, which regulate appetite, food intake, and energy expenditure through unknown signaling pathways @naturecomms.bsky.social www.nature.com/articles/s41... #obesity #genetics

submitted 82 days ago • 0 comments

Geneticist @maartenlarmuseau.bsky.social tackles a touchy question: How often are children genetically unrelated to their presumed fathers?

submitted 100 days ago • 0 comments

Genetic architecture in Greenland is shaped by demography, structure and selection www.nature.com/articles/s41...

submitted 121 days ago • 0 comments

Nature publishes the deeply flawed "Black Death selection paper" in Oct 2022. A preprint refuting it is uploaded to bioRxiv Mar 2023. Now, 2 years later(!), Nature finally publishes the preprint as "matters arising". Number of accesses on the original paper since: 200k. Number of cites: 173. 1/2

submitted 115 days ago • 1 comment

Interesting thread on the sharing of scientific articles on Twitter vs Bluesky. For better or worse, the emigration of scientists from Twitter is real and ongoing:

submitted 128 days ago • 0 comments

Complete human recombination maps www.nature.com/articles/s41... - continuation of 25 yeas of work in building recominbation maps.

submitted 143 days ago • 1 comment

Just spent $5 to export my Twitter posts to this Bluesky account with blueark.app. Quite happy with the results. Pros: quick, easy, keeps tweet date, keeps images Cons: doesn't export tweets that quoted/replied to other accounts, so only exported 1/6 of my total posts; doesn't export poll reponses

submitted 144 days ago • 0 comments

How population stratification makes environments look like genes. A short 🧵:

submitted 145 days ago • 7 comments

I can't help but feel that this wagon-circling and fact-massaging reflects a pattern of behaviour by the leadership of Science - of treating the science world as a kind of guild whose interests must be advanced, of explicitly leveraging the institution to promote certain political views as truth.

submitted 148 days ago • 1 comment

EXTREMELY cool and demonstrates clearly the promise of deep learning + bio. www.nature.com/articles/s41...

submitted 150 days ago • 4 comments

Great perspective on the near-term viability of human embryo editing. Much-needed nuance to the modelling exercise presented today in Nature.

submitted 157 days ago • 1 comment

In Top10 @ScienceMagazine 2024 breakthroughs of the year: Reconstructing ancient pedigrees + IBD segment sharing in aDNA. 😮😊 🎉 Great write-up by @spoke32.bsky.social ! 👏👏

submitted 166 days ago • 0 comments

Silicon Valley has lost its mind about genetics. Huge interest in short-sleep etc variants (candidate gene nonsense), embryo selection for cognitive traits (extremely low real-life predictive ability), and Jiankui He (charlatan whose human gene editing totally failed AND made many off-target edits)

submitted 174 days ago • 3 comments