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marinalusic.bsky.social
PI @ CIID, Heidelberg, and @DZIF. Mom of two and scientist in love with nuclear architecture - NPC- RNA processing, metabolic switches in infected immune blood and brain cells 🧬🔬🧬🦠🧫
34 posts 1,167 followers 583 following
Prolific Poster

Online Now: The nucleolar granular component mediates genome-nucleolus interactions and establishes their repressive chromatin states Online now:

Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3

Deaths from heart disease down 75%, that’s NIH. Deaths from stroke down 75%, that’s NIH. HIV/AIDS no longer a death sentence, that’s NIH. 99% of FDA approved drugs in the last decade, that’s NIH. Please show this video to anyone who doesn’t understand why the NIH is so important.

Now online! Integrator loss leads to dsRNA formation that triggers the integrated stress response

Great work on 3D chromatin from @becklab.bsky.social led by @jpkreysing.bsky.social and @sergiocruzleon.bsky.social in primary human resting CD4 T cells! Very happy to have contributed !

An excellent view of the current state of the affairs in US science by Paul Bieniasz www.theguardian.com/commentisfre...

From enhancer hijacking to ecDNA and onco-condensates – we review how changes in nuclear architecture drive oncogenic gene expression by disrupting enhancer–promoter communication. doi.org/10.1002/ijc..... Kudos to Isabelle Seufert, @claire-vrgs.bsky.social and Sina Wille 👏

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇

New paper alert! Anton Goloborodko and international collaborators describe the rulebook defining how molecular motors work together to package and rearrange the DNA for cell division: https://imba.science/41YiAPn

universities and all americans need to band together to fight this threat to american innovation. China is already excellent at biomedical research and this is just hurting american research.

Predictably, it’s our turn to be viciously targeted by this ruthless, short-sighted and spiteful administration. We will RESIST and I have trust in Cornell leadership to mount a potent defense to protect our community and values and ultimately prevail over this evil. www.reuters.com/world/us/us-...

'Bluesky has overtaken its flailing rival X in hosting posts related to new academic research, indicating the platform is fast becoming the go-to place for scholars to share their work.'

Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres. #theconferencetoendallconferences Register now: woodstock.img.cas.cz

For decades, the US has been a magnet for global research talent. According to a poll we ran, many are considering leaving & Europe is advertising itself as a destination for embattled US scientists. A brain drain would impoverish the US & diminish global science 🧪 www.nature.com/articles/d41...

‘One of the darkest days’: NIH purges agency leadership amid mass layoffs www.nature.com/articles/d41...

🚀 New Paper Alert! Our latest @natrevmcb.bsky.social explores how nuclear and genome organization drive DNA double-strand break repair! 🧬 📖 Free access: rdcu.be/edViW Please 🔄 ❤️

Almost 17 years after opening our yeast cell division lab, our first transcription paper in mouse embryonic stem cells! www.science.org/doi/10.1126/...

What I love most about science are unexpected discoveries-finding what was thought not to exist or imagined differently, even against our hypotheses. We uncover them by following curiosity & intuition. That’s why we’re hosting WoodstockNightScience, to spark bold ideas. Join us! #Science #Innovation

Applications are open for new Schaller Research Group Leader Positions in the field of Infectious Diseases at Heidelberg University. These generously funded positions of 5+2 years are a great opportunity for young virologists! Find out more here: www.klinikum.uni-heidelberg.de/fileadmin/in...

Diversity is our greatest asset, even if the government disagrees… They not like us! POC in STEM are here to stay. They tried to rig the game but you can’t fake influence! Mustard on the [Be][At] bro. Happy Black History Month!

www.science.org/content/arti...

Giving infectious disease research a break, as promised by the MAHA agenda. Let's break down what exactly this Executive Order is *really* saying. Fortunately, I speak fluent anti-vax grifterese & can translate. www.whitehouse.gov/presidential...

Want to lead a research group at a Max Planck Institute – with a #tenuretrack position & substantial resources? Apply for the Lise Meitner Excellence Program by @maxplanck.de. The program aims to promote exceptionally qualified #WomeninScience. Deadline: April 8, 2025 www.mpg.de/lise-meitner...

www.npr.org/sections/sho... It is time to think of measures to prevent this from happening in germany and EU. @dfg.de

Our paper on Stopless-ORF Circular RNAs (socRNAs) is now out in Cell. By high-res tracking and comparing translation by either single or multiple ribosomes, we find that ribosomes cooperate to overcome pausing to ensure fast and efficient translation www.cell.com/cell/fulltex...

Our paper is out! We delevoped a method to follow individual translating ribosomes for hours in living cells, and discovered that ribosomes are great friends and help each other in problematic situations: www.cell.com/cell/fulltex...

Thank you @anthrofuentes.bsky.social for this call to action for scientists @science.org

www.theguardian.com/world/2025/f...

Federally funded researchers may be forced to remove terms from their research, like gender. "If no data exist to prove that a health issue concentrates within a particular community, that provides a justification to cut funding," writes Katherine Wu. www.theatlantic.com/health/archi...

The Nets, 1882

Extremely timely #ZOiS_Spotlight on #protests in #Serbia by my colleague @ivodinev.bsky.social. A typical case of a protest that starts with students and then mobilises the middle of society? In my view not getting enough attention yet. ⬇️

Protest in Zürich in support of the students for Novi Sad. #novisad #serbia #protest #zurich

Students in Serbia have formed the largest student movement in contemporary Europe, growing into a massive force with support from various social groups. In this text, I explore what is going on in Serbia. Please read & share, thank you! 🤝 #students #Serbia #protest

Finally, 🇷🇸 #serbiaprotest is making it into major 🇩🇪 news. About time! These democratic protests deserve far more attention. @tagesthemen.bsky.social @draganadjurica.bsky.social

On February 2, Georgians plan to take their protest even further by blocking the main highways leading into Tbilisi. The protest movement drew inspiration from the brave people of Serbia. #GeorgiaProtests 📸: #SerbiaProtests, Jan 28, 2025, SkyNews

Novi Sad, Serbia. Remarkable footage captured last night in Serbia’s second largest city. Tens of thousands in another massive anti-government protest. (🎥 Kreni Promeni)

This is one of the first coverages about the peaceful students protests in Serbia, which converged yesterday in the city of Novi Sad, where three months ago a concrete canopy of the newly inaugurated railway station collapsed to kill 15 people www.theguardian.com/world/video/...

Taking responsibility: Asilomar and its legacy | Science www.science.org/doi/10.1126/...

This will have a very tragic impact

Bluetorial-A dream and a bit of a nightmare Serving as Editor-in-Chief at Science was fascinating. I greatly enjoyed working with talented and committed editorial, news, graphics, and production staff. But the inside look into scientific publishing and AAAS was also deeply disillusioning.

NIH vet who criticized Fauci during the pandemic is in as acting director Ft. @joho.bsky.social & @jeremymberg.bsky.social 🧪🔬 #medsky www.statnews.com/2025/01/24/t...

Good morning, all! What an incredible selection of papers in #cancermetabolism and #mitochondrialbiology! Check it here: biomed.news/bims-camemi/... @biomednews.bsky.social "Anything you have imposed on yourself to be unhappy is a concept. So, give it away." -H. W. L. Poonja

Breakthrough of the Year is lenacapavir, which provides six months of HIV prevention in a single injection. This is the third time Science has named an HIV/AIDS intervention as the Breakthrough of the Year. Here's my editorial with links to the full package and quotes from Angels in America.

Cool thread about how the HIV genome enters the nucleus--it remains within its viral capsid and busts into the nucleus by pushing through and disrupting the nuclear pore. Incredible that we're still learning new things about this important human pathogen 🧪