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martinhumphries.bsky.social
Professor of Biochemistry, University of Manchester. Career interest in mechanisms of cell-matrix adhesion. Current interest in mechanosensing in pancreatic cancer and vascular dementia.
431 posts 1,599 followers 314 following
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Welcome!

Stegosaurus was already a fossil by the time that T. rex lived

Cancer vaccines will be a big part of the future of immunotherapy. A new, super review @thelancet.com www.thelancet.com/journals/lan...

We are looking for a postdoctoral fellow to come work with us: www.cruk.manchester.ac.uk/career/mi-25... Please reach out

I’d love to know what Macron knows and what he just told Meloni. That’s one hell of a reaction. #G7

Swindon

Microbial life is the foundation of all living systems. A new @asm.org report, with our Director Susana Coelho part of the steering committee, explores 3 key steps in Earth’s history—from simple cells to complex life— and what it means for future science. Read more: s.gwdg.de/Dzn885

Antoku, S et al. The nucleus activates mechano-responsiveness via FHOD-associated LINC complexes. bioRxiv posted 15 June 2025 doi:10.1101/2025.06.13.659598. www.biorxiv.org/content/10.1...

[Exit King.]

Looking forward to this (online unfortunately)

Lee WN, et al. Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6. Adv Sci (Weinh). 2025 Jun 10;:e01078. [Epub ahead of print] PMID: 40492509

De, A. et al. Single Cell Spatial Profiling Identifies Region-Specific Extracellular Matrix Adhesion and Signaling Networks in Glioblastoma. bioRxiv posted 9 June 2025 doi:10.1101/2024.10.31.621280. www.biorxiv.org/content/10.1...

Cheng X & Case LB. Condensates control the actin cytoskeleton. Dev Cell. 2025 Jun 9;60(11):1519-1520. PMID: 40494278 🤔

LAPD fired rubber bullets at Australian journalist @laurentomasi.bsky.social

White House: "Violent mobs have attacked ICE officers and Federal Law Enforcement Officers." LAPD: "Today, demonstrations across the City of Los Angeles remained peaceful."

“Tasted a little tear gas— tasted like fascism”

I very much welcome the announcement of the Local Innovation Partnerships fund, with ~ £30m funding for industry facing, translational research in each of 7 English city-regions, + places in Wales, Scotland & NI, allocated towards locally determined priorities. www.gov.uk/government/n...

Thanks Patrick Vallance

Everyone should read this www.theguardian.com/commentisfre...

😂

The COVID-19 vaccines are the closest humans have come to a scientific feat like blowing up an asteroid headed to Earth in real time and saving millions, if not tens of millions, of lives. And conservatives are like, "Witch!!"

I watched this happen on the morning of 4 June 1989 in Chang’an Avenue, near Tiananmen Square, the morning after the night’s massacre. Don’t believe the propaganda lie that no massacre took place: I saw 40 people killed in front of me before giving up counting in despair. pic.x.com/zhqZhT6iPB

I decided to become a journalist aged fifteen after reading ‘1984’ and being appalled at the thought that governments could rewrite history. Orwell knew the USSR did it. Now China pretends the Tiananmen massacre didn’t happen. It did. I was there, and saw it for myself.

Best science channel that you can find on YouTube. Visit it, you'll thank me later. youtube.com/@howtown?si=...

🧵👏🏻

Spring 2025 was warmest and sunniest on record for UK Read more here from Liam Dutton:

I'm helping organize the 2026 Signaling by Adhesion Receptors GRC and would love your speaker suggestions! We're especially looking for assistant professors or new community members who would enrich the meeting. Send your suggestions via PRIVATE message or email. Thanks!

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

Chen Y, et al. Interplay between material properties and cellular effects drives distinct pattern of interaction of graphene oxide with cancer and non-cancer cells. J Nanobiotechnology. 2025 May 30;23(1):393. PMID: 40442703

👏

Wow

Shah SR, et al. YAP controls cell migration and invasion through a Rho GTPase switch. Sci Signal. 2025 May 27;18(888):eadu3794. PMID: 40424361

Excellent!

🤣

A big step forward vs cancer www.nature.com/articles/d41...

Conway JRW, et al. @ivaskalab.bsky.social Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells. Nat Cell Biol. 2025 May 26;. [Epub ahead of print] PMID: 40419795

Too much protein in the diet appears to carry a risk of atherosclerotic heart disease secondary to leucine's effect. An important report considering recent advocacy for very high-protein diets. @natmetabolism.nature.com nature.com/articles/s42...

That's been there a while! #YorkshireDales

If your test for ground-breaking discoveries can’t detect the discovery of RNAi, or of CRISPR-Cas9, or the cryoEM resolution revolution or Alphafold2, maybe it’s not a very good test. www.nature.com/articles/d41...

💥 NEWS: McDonald's shareholders voted Tues. to reject an anti-DEI proposal, 99-1 percent. McDonald's Board said the proposal "unduly interferes" with the company's "flexibility and judgment." MCD: "Our success in the future builds on our history of embracing diversity as a competitive advantage."

Interesting 🧵

💥💥💥 www.bbc.co.uk/news/article...

The GRC on Fibronectin, Integrins and Related Molecules earlier this month was a fantastic meeting. Good work @tanentzapflab.bsky.social and @sarawickstrom.bsky.social for organising. www.grc.org/fibronectin-...