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maxewilkinson.bsky.social
PhD @MRC_LMB, now post-doc at @MIT, dabbler in cryoEM. Keen on spliceosomes. Now also keen on reverse transcription. Kiwi.
11 posts 490 followers 98 following
Getting Started

Nice visit to the lovely Princeton campus. Could not be prouder of @automnenine.bsky.social. For those who are looking for a postdoc, there are exciting opportunities to join his lab!

Ridiculously good work by George on LINE-1 retrotransposition! Also the paper is an inspiring read - there's some really super biochem in it

we recently found some really neat RNA-guided DNA-cutting systems in phages. Despite remarkable similarities to CRISPR systems, including encoding guide RNAs in arrays, they appear entirely evolutionarily distinct (but definitely related to snoRNAs 🤓) We decided to call them TIGR-Tas systems 🐯

please go check out this glowing pink blob and what it does to the shiny gold blob (it's a spliceosome! Truly it was a nostalgic pleasure to help out with this paper, a super fun collaboration with @uwmadisonrna.bsky.social & Kathy and Karli)

gonna start shamelessly crossposting some of my molecular movies from the Other Place. Starting with my favourite: showing how wacky reverse transcription can defeat viruses. Bonus: some noises 🎹🎻

Our fly brain connectome papers are now live (www.nature.com/immersive/d4...), and is getting traction (www.bbc.co.uk/news/article...). With ~139k neurons, >8k cell types, synapses annotated, transmitters predicted, ~134 evo-devo units denoted, so much is now possible in the fly.