Profile avatar
maxfus.bsky.social
Asst. Prof. Uni Groningen 🇳🇱 Comp & Exp Biochemist, Protein Engineer, 'Would-be designer' (F. Arnold) | SynBio | HT Screens & Selections | Nucleic Acid Enzymes | Biocatalysis | Rstats & Datavis https://www.fuerstlab.com https://orcid.org/0000-0001-7720-9
325 posts 1,687 followers 730 following
Regular Contributor
Active Commenter
Posts 19 Comments 31

✨Cradle is hiring protein+ML researchers!✨ We operate ML for lab-in-the-loop lead optimization across all industries (pharma, synbio, ...), modalities (antibodies, enzymes, ...), properties (binding, activity, ...) We're a scaleup and already relied upon by 4 of the top 20 big pharma. Apply here!

submitted 11 days ago • 1 comment

1/At the #HoffmanLab lab meeting, we often have tech talks describing useful tools for other lab members. Since they might also prove useful for others, we've been posting almost every #HoffmanLabTechTalk for years. 🧪🧬💻

submitted 382 days ago • 2 comments

Springer-Nature launched a series of "Discover" journals that closely mimic MDPI titles -- sharing *identical* journal names, and likely similar business model. What is going on, and why researcher will - as always - fall for it? A 🧵 the-strain-on-scientific-publishing.github.io/website/post...

submitted 14 days ago • 9 comments

1/10 New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang's Lab! We uncover the unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: www.biorxiv.org/content/10.1...

submitted 17 days ago • 3 comments

Its 2025 and two atoms STILL can exist in the same space according to AF3

submitted 26 days ago • 5 comments

www.wehi.edu.au/careers/make... WEHI is looking for new lab heads! New and experienced lab heads welcome. Check out the ad, consider applying and share. We’re a collaborative bunch, in Australia, with fabulous technology, great colleagues at a values-driven organisation. @wehi-research.bsky.social

submitted 46 days ago • 0 comments

We are in the market for a benchtop FACS machine. Does anyone have recommendations for a reliable, low-maintenance instrument? We are mostly sorting mouse cells. We are currently considering the Sony SH800, Bio-Rad S3e, or similar options.

submitted 25 days ago • 0 comments

🚀 Excited to release BoltzDesign1! ✨ Now with LogMD-based trajectory visualization. 🔗 Demo: rcsb.ai/ff9c2b1ee8 Feedback & collabs welcome! 🙌 🔗: GitHub: github.com/yehlincho/Bo... 🔗: Colab: colab.research.google.com/github/yehli... @sokrypton.org @martinpacesa.bsky.social

submitted 26 days ago • 1 comment

Planning to apply for #research #funding from the ERC? From the next application rounds, expect changes to the: • proposal structure • evaluation process • extra funding you can request • eligibility for Starting & Consolidator #Grants (from 2027) More 👇 europa.eu/!RPHWvv

submitted 27 days ago • 3 comments

1 plant hormone receptor ☘️ 3,500 mutants, to single-site saturation 🧬 >45,000 binding and abundance measurements 📶 Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.

 www.biorxiv.org/content/10.1...

 With @benlehner.bsky.social [1/7]

submitted 27 days ago • 3 comments

Fixed that for you! Original (very awkward) color scale did not reflect how much of an outlier NL is. Picture changes for 3yr - school age though. Of course this data does not distinguish between day care vs grandparents etc. Not that the latter is an option for expats, anyway 😶‍🌫️

submitted 27 days ago • 0 comments

Roche has given more details of their SBX NGS technology: it'll be called Axelios, and we know it's aimed at competing against Illumina SBS technology, the technology the San Diego company acquired from Cambridge UK Solexa. I'll give you a second to catch up with it... Axelios vs Solexa....

submitted 28 days ago • 2 comments

I spent way too long on this but I made a small benchmark for OCR of biological sequences. It's pretty incredible how poorly everything I tried works. Maybe by posting a benchmark it will lead to finding something out there that works! github.com/hgbrian/bio_...

submitted 29 days ago • 1 comment

New paper from my group rdcu.be/eoaRr "Trinucleotide substrates under pH–freeze–thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme" in Nature Chemistry — great collaboration with attwaterlab.uk.

submitted 31 days ago • 0 comments

NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.

submitted 38 days ago • 37 comments

We are recruiting a junior group leader in computational structural biology. Spread the news! www.nature.com/naturecareer...

submitted 34 days ago • 0 comments

Proud of Harvard for pushing back, exercising some creativity, and, maybe, helping folks get some needed education. Harvard is making many of their online government courses FREE. I just signed up for "Citizen Politics in America". They even asked me my Gender. pll.harvard.edu/subject/gove...

submitted 36 days ago • 14 comments

🚨 preprint 2️⃣ this month: our (purely experimental🧪) venture into #ChemBio We prouldy present: ADD-tagging of proteins (or "ADDing") —a super convenient enzymatic technique to install click chemistry handles on proteins. Led by superstar @wahyuwidodo.bsky.social www.biorxiv.org/content/10.1... A 🧵👇🏽

submitted 40 days ago • 4 comments

Discover 𝗖𝗮𝘃𝗲𝗿 𝗪𝗲𝗯 𝟮.𝟬! Our user-friendly web server 🧬 💻analyses protein tunnels, ligand transport, and flexibility —perfect for drug discovery, protein engineering, and more. Now with virtual screening of approved drugs and custom datasets. Try it now: loschmidt.chemi.muni.cz/caverweb

submitted 44 days ago • 1 comment