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neurome.bsky.social
Neuronal epigenomics. Dad jokes my own.
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Posts 24 Comments 18

I wrote a review of a recent paper on false discovery and multiple testing correction. liorpachter.wordpress.com/2025/06/16/r...

submitted 14 days ago • 7 comments

Great to see attention being paid to rigor in neuroscience methods.

submitted 18 days ago • 1 comment

My statement on what's unfolding in Los Angeles.

submitted 22 days ago • 507 comments

Always pseudobulk, always correct for multiple comparisons, and always consult with a biostatistian. www.nature.com/articles/s41...

submitted 26 days ago • 0 comments

www.nature.com/articles/s41... The engram is still out there, waiting to be rigorously discovered!

submitted 26 days ago • 0 comments

Very happy to see our comment about scRNAseq methods and rigor finally published. Now more than ever, science must be an example of integrity and self-examination. If we abandon rigor, we will be even more isolated and vulnerable.

submitted 26 days ago • 0 comments

Hard to process the news about Harvard and international students. Other universities should stand in solidarity with our colleagues who are being persecuted.

submitted 38 days ago • 0 comments

Francis Crick speculated that DNA modifications might be key to memory.... but synaptic molecules are specific to individual neural connections

submitted 45 days ago • 0 comments

Genuine question: what will all the talented US and international people who would have gone into science do instead? Real estate?

submitted 59 days ago • 0 comments

"A report by economists at American University in Washington DC estimates that a 50% reduction in federal science funding would reduce the US gross domestic product by approximately 7.6%." Science is an amazing engine of economic activity and progress for the US ... or at least it was.

submitted 60 days ago • 1 comment

First they came for the data, and I did not speak out... because I was not data Then they came for the models, and I did not speak... because I was not a model. Then they came for the scientists, and there was no one left to speak for me.

submitted 82 days ago • 0 comments

Science not Silence. (Kudos to the students on my hallway who put these up)

submitted 89 days ago • 0 comments

I signed and urge others to sign as well.

submitted 91 days ago • 0 comments

I'm ashamed of my country

submitted 122 days ago • 0 comments

So who is leading the resistance? We have no time to lose.

submitted 130 days ago • 0 comments

Spent today hearing inspiring and exciting science from fellow members of an NIH Consortium studying HIV and opioid effects on the 🧠. A reminder of what we have to lose if the US abandons our scientific enterprise.

submitted 139 days ago • 0 comments

So when we "buy" Greenland, will we call it Trumpistan? Donaldland? Maganesia? The Panama Canal will be called Trump's Trickle.

submitted 153 days ago • 0 comments

My awesome colleague @seantrott.bsky.social quoted on understanding the nature of our new robot overlords in @nytimes.com www.nytimes.com/2024/12/16/o...

submitted 195 days ago • 1 comment

Low tide in La Jolla today

submitted 197 days ago • 0 comments

Calcium imaging of Climbing Fiber complex spikes in mice performing skilled movements... Ahh this brings back fond memories for me :). Very cool.

submitted 200 days ago • 1 comment

What's the best response to bullshit Truth posts? Send a BS (bluesky) about it right here. (Skeet is not doing it for me)

submitted 208 days ago • 0 comments

I used to think the US was a country that valued and invested in science. Not sure how to keep up a brave face and try to inspire/encourage the next generation when we're nominating antiscience quacks to lead NIH.

submitted 210 days ago • 0 comments

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. www.nature.com/articles/s41...

submitted 215 days ago • 9 comments

Today I learned that the Watson & Crick 1953 paper was not peer reviewed. Editor just published it. Good thing too, because Reviewer 2 would have objected to the small sample size (n=2 helices)

submitted 215 days ago • 0 comments