opentargets.org - Profile | ThreadSky | a Reddit-style client for Bluesky

👀 We're gearing up for the next release of the Open Targets Platform! The team will walk you through the latest updates in our LinkedIn Live on 19 June, 3pm UK time You'll then have the opportunity to ask us your questions about the Platform See you there! www.linkedin.com/events/25-06...

submitted 5 days ago • 0 comments

Open Targets Genetics will be deprecated on 9 July 2025 You will no longer be able to access genetics.opentargets.org. An archive of the data will be accessible through the EMBL-EBI FTP We are happy to help with questions or concerns on the Open Targets Community: community.opentargets.org

submitted 30 days ago • 1 comment

👇Join us this afternoon for a Q&A session on the Open Targets Platform!

submitted 32 days ago • 0 comments

“This work addresses a biological question of key importance with creative approaches" Diederik Laman Trip and @pedrobeltrao.bsky.social describe their new method to predict protein associations based on co-abundance in a research briefing, published today 🧬🖥️ www.nature.com/articles/s41...

submitted 33 days ago • 1 comment

Teamwork is crucial for proteins. Little is known, however, about which protein teams are actually active in which tissues. A new large-scale study by systems biologists at ETH Zurich is now redrawing the map. ethz.ch/en/news-and-...

submitted 33 days ago • 1 comment

🎂 The Open Targets Platform turns 10 this year! To celebrate this milestone, join us in person or online for a two-day hackathon exploring data, analyses, and tools for target discovery 🖥️🧬 You can already submit a project idea: www.opentargets.org/hackathon Registrations will open in June

submitted 37 days ago • 1 comment

Join us for a live Q&A on the Open Targets Platform, and the genetics data in our latest release! 🧬🖥️ We will review and prioritise questions submitted in advance: forms.gle/EA75gDdNwjxk... Register: embl-org.zoom.us/webinar/regi...

submitted 38 days ago • 0 comments

An atlas predicting protein interactions in 11 human tissues created by @pedrobeltrao.bsky.social's team at @imsb-eth.bsky.social will help uncover cell-type specific functions, elucidate disease mechanisms, and choose safer targets for drug discovery 🧬🖥️ blog.opentargets.org/an-atlas-of-...

submitted 39 days ago • 0 comments

A tissue-specific atlas of protein–protein associations enables prioritization of candidate disease genes - @pedrobeltrao.bsky.social @imsb-eth.bsky.social @opentargets.org go.nature.com/3Z1q0PM

submitted 42 days ago • 2 comments

Out today in Nature Biotechnology! This Open Targets project created an atlas of tissue-specific protein associations for 11 human tissues, furthering our understanding of cell-type and tissue-specific function, and helping to prioritise more specific—and potentially safer—drug targets 🧬🖥️

submitted 43 days ago • 0 comments

Out now! An Open Targets team reviewed the use of Natural Language Processing in drug discovery, exploring Named Entity Recognition, Knowledge Graphs, Large Language Models, and the strengths and weaknesses of different methods for NLP tasks 🧬🖥️ www.tandfonline.com/doi/full/10....

submitted 44 days ago • 0 comments

New to the Open Targets Platform? Want a quick primer on our new genetics data? The recording of last week's webinar is now available to watch on YouTube! www.youtube.com/watch?v=x7vA...

submitted 45 days ago • 0 comments

Have a question about our latest release? Join us for a live panel discussion on May 13! This interactive Q&A is your opportunity to ask questions about using the Platform, and in particular the genetics data and analyses we introduced in March Register now! embl-org.zoom.us/webinar/regi...

submitted 46 days ago • 0 comments

Introducing The T Cell Show! 📺👩‍🔬 Follow along as a T cell interviews the immune system while a B cell undertakes a journey through the body, highlighting the specific immune functions of various organs.

submitted 51 days ago • 1 comment

On April 23, we'll be (re)introducing the Open Targets Platform — join us! The webinar will walk through the different capabilities of the Open Targets Platform, including our new variant, study, and credible set pages. www.ebi.ac.uk/training/eve...

submitted 60 days ago • 0 comments

A really nice thread (as always from Eric) demonstrating the utility of the new @opentargets.org platform with a focus on HbA1c

submitted 61 days ago • 0 comments

Going to #ISMBECCB2025? 🧬🖥️ We're part of a full-day tutorial on genomic variant interpretation and prioritisation for clinical research Sound interesting? Registration is open now — see you there!

submitted 66 days ago • 0 comments

Excited to share our "Associations on the Fly" paper in Oxford Bioinformatics! 🧬🔍 In @opentargets.org we built this tool to visualise multi-level data on a single screen, helping researchers navigate complex evidence without switching context. Check it out: academic.oup.com/bioinformati...

submitted 66 days ago • 0 comments

Out now in Bioinformatics! @carcruz.dev and Annalisa Buniello present our new interactions view: Associations on the Fly "Our primary goal in creating AOTF was to build a tool that could represent multiple levels of analysis on the same screen." academic.oup.com/bioinformati...

submitted 67 days ago • 1 comment

Big thanks to the community for the great feedback we are receiving on the spring @opentargets.org Platform release. There are many positive and new ideas for improving our scientific interpretation and products. Feedback is a critical aspect of an open project's lifecycle. Please keep it coming 🧬🖥️

submitted 78 days ago • 0 comments

The @ebi.embl.org Thornton Building was officially opened last week by Lord Vallance of Balham, the UK’s Minister for Science, Research and Innovation Open Targets' new home is named for Professor Dame Janet Thornton, a pioneer in bioinformatics

submitted 79 days ago • 1 comment

Register for our webinar on 23 April! We will introduce the capabilities and use cases of the Open Targets Platform, including our new variant, study, and credible set pages released last week 🧬🖥️ www.ebi.ac.uk/training/eve...

submitted 81 days ago • 0 comments

There are many improvements and new features in the latest @opentargets.org release! Genetics here we go 🚀 New data visualizations, accessible color pallets, and full UI refresh. Not to say, the addition of @observablehq.com Plot.js, the upgrade to @vite.dev v6. React Router v7 🔜

submitted 86 days ago • 2 comments

Come join our adventure @sangerinstitute.bsky.social 👇🏾

submitted 86 days ago • 0 comments

Open Targets Platform 25.03 is finally here! 🌼 This update brings in variant, study, and credible set information, uniting the Open Targets Platform and Open Targets Genetics into a one-stop shop for human genetic and target discovery information. blog.opentargets.org/open-targets...

submitted 86 days ago • 1 comment

We're recruiting! ➡️ (Senior) bioinformatician: join a collaborative project with @mhaniffa.bsky.social and Mo Lotfollahi, supporting the analysis of single-cell and spatial transcriptomics studies to train AI-based foundation models Apply by 25 March sanger.wd103.myworkdayjobs.com/en-US/Wellco...

submitted 88 days ago • 0 comments

At the first Integration Day of 2025, we were joined by Joseph Powell from the Garvan Institute and Tomas Fitzgerald from EMBL-EBI Thank you to both speakers for their time and insights on the topic of drug exposures, and for everyone who joined the day in person and online!

submitted 93 days ago • 0 comments

👀 Not long now until the spring (25.03) Platform release… This will introduce variant, study, and credible set data, effectively merging Open Targets Genetics with the Open Targets Platform 🖥️🧬 We're working on documenting the changes — do you have any questions or concerns that we can answer?

submitted 100 days ago • 0 comments

New preprint from our group @ebi.embl.org and the Vidal-Puig group! We combined pseudotemporal ordering of cross sectional MASLD patient data with network analysis to describe the disease progression and identify a signature of 24 plasma biomarkers for patient staging www.biorxiv.org/content/10.1...

submitted 146 days ago • 1 comment

In a recently published preprint, @epetsalaki.bsky.social, Toni Vidal Puig and Irene Papatheodorou’s groups established a disease trajectory for MASLD, and found a set of 24 plasma biomarkers that could be used to predict a patient’s disease stage www.biorxiv.org/content/10.1...

submitted 102 days ago • 1 comment