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polybiorf.bsky.social
501(c)3 transforming how #LongCovid, #ME/CFS & Lyme+ are studied, diagnosed, and treated. Leading the #LongCovid Research Consortium.
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PolyBio’s Spring Symposium is approaching fast—on May 16, watch exciting project updates on clinical trials, tissue pipelines, immune & metabolism findings on infection-associated chronic illnesses. Sign up now: us02web.zoom.us/webinar/regi...

submitted 10 days ago • 2 comments

Post-treatment Lyme Disease patients with chronic pain in the US—consider participating in this decentralized study (completely virtual). It’s run via the CoRE clinic under the direction of Drs. David Putrino and Amy Proal @putrinolab.bsky.social @coresinai.bsky.social

submitted 16 days ago • 0 comments

The PolyBio-supported study on elevated plasma proteins associated with breathlessness in Long COVID was featured in an article in Technology Networks : www.technologynetworks.com/tn/news/long...

submitted 17 days ago • 1 comment

Calling all Long Covid, ME/CFS and Post-Treatment Lyme patients in the Boston area! This PolyBio-supported study is now seeking participants. Participants must be able to attend an in-person visit at Brigham & Women’s hospital in Boston to participate. Email [email protected] if interested

submitted 30 days ago • 0 comments

We’re truly excited that the PolyBio supported Low-dose Rapamycin trial is now recruiting in the NYC area. Interested in learning more? Here’s the full study summary: polybio.org/projects/lon...

submitted 33 days ago • 1 comment

BREAKING: Development of a spike protein-specific radiolabeled antibody used with PET imaging shows presence of spike in brain & lungs of macaque monkeys 3 months post-COVID; provides new viral reservoir detection opportunity for long COVID: www.nature.com/articles/s41...

submitted 51 days ago • 8 comments

Dr. Rigel Chan is investigating SARS-CoV-2’s impact on the development of #Alzheimers. His work has found that S protein levels in cells aren’t associated with AD, “but exposure to antigens like Spike may alter the conditions such that [patients] become more susceptible to HSV1.”

submitted 58 days ago • 1 comment

Dr. Zian Tseng has been studying sudden cardiac deaths since 2011–and is now using those data to compare to SCDs post-COVID. “A post-2020 person who recovered from COVID… died suddenly from their acute myocardial infarction. We found SARS-CoV-2 Spike RNA in their brain [tissue].”

submitted 60 days ago • 1 comment

Dr. David Price is investigating the role of lung dysfunction in Long Covid: “We’re sampling bronchoalveolar lavage fluid and transbronchial biopsies… what we plan to do is metagenomics, metatranscriptomics & RNA seq… to get some idea of the pathogenesis of LC at the site of initial infection.”

submitted 68 days ago • 1 comment

Dr. Petter Brodin is leading a project investigating the genetic determinants of Long Covid. “We’re currently looking for genetic variants that could explain why [Long Covid patients] have what we think is impaired antiviral immunity, leading to viral persistence.”

submitted 71 days ago • 1 comment

Dr. Akiko Iwasaki, who has led work on the role of human endogenous retroviruses (HERVs) in chronic diseases i.e. lupus, is now investigating the role of HERVs in Long Covid.

submitted 74 days ago • 4 comments

“We’re trialing a low dose of Rapamycin once a week… which may have an immune-supporting effect,” Dr. Proal explained last week via the CoRE clinic. There are a couple studies that show this low dose could improve signalling of interferons… used to control viral infections.”

submitted 81 days ago • 3 comments

Dr. Amy Proal, Scientific Director of the CoRE Clinic at Mount Sinai, discusses viral persistence as a driver of ME/CFS with Dr.s Raven Baxter & David Putrino: “[research] finds the RNA backbone & protein of enteroviruses in ME/CFS gut tissue.” @coresinai.bsky.social

submitted 88 days ago • 7 comments

PolyBio president Dr. Amy Proal outlines the direction that research must take to address long COVID in her new op-ed for @latimes.com: “The urgency of long COVID is a call to arms for government and private funders to help bring medications and protocols to the people who need them.”

submitted 91 days ago • 0 comments

Dr. Ed Breitschwerdt is investigating the proportion of Long Covid, ME & EDS patients with Borrelia, Babesia and Bartonella in their blood using a highly accurate ddPCR assay. “We’ve seen every combination of infection, from only 1 organism to co-infection with all 3.”

submitted 93 days ago • 1 comment

Post-COVID-19 condition (also known as long COVID) is a debilitating disease state following SARS-CoV-2 infection. In @thelancetinfdis.bsky.social, authors outline major considerations for clinical trials targeting SARS-CoV-2 persistence in long COVID: tinyurl.com/bdfyn74m

submitted 94 days ago • 4 comments