rsankowski.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Masterful #dataviz on the current State of #Science #Funding in the US Trump Has Cut Science Funding to Its Lowest Level in Decades - The New York Times www.nytimes.com/interactive/...

submitted 1 day ago • 0 comments

Incredible approach to use allogenonic nonhuman regulatory T cells for #brain disorders. At least it’s safe but I’m curious to see if it works in many patients Clinical Safety and Preliminary Efficacy of Regulatory T Cells for ALS | NEJM Evidence evidence.nejm.org/doi/full/10....

submitted 2 days ago • 0 comments

A Perspective on a dynamic and multimodal framework to define microglial states from @rsankowski.bsky.social and Marco Prinz www.nature.com/articles/s41...

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#microglia and other tissue #macrophages are highly plastic. This makes them look differently depending on their respective context. Granular methods like #single-cell sequencing are merely snapshots that may simplify the complexity found in the tissue. In our perspective in @natneuro.nature.com

submitted 4 days ago • 1 comment

A few recent publications on Spatial Multi-Omics www.nature.com/articles/s41...

submitted 5 days ago • 1 comment

New CAJAL course incoming! Applications are now open #CancerNeuroscience (22 Sep – 10 Oct 2025) at the Bordeaux School of Neuroscience! 🔗More info: cajal-training.org/on-site/canc... @varunvenkatesh.bsky.social, #AntonioPagano

submitted 5 days ago • 0 comments

Meticulously executed study o leptomeningeal metastasis-induced immunological changes at the brain border regions. Kudos to @meningojan.bsky.social and team! I learned a lot: Interferon-γ orchestrates leptomeningeal anti-tumour response | @nature.com www.nature.com/articles/s41...

submitted 8 days ago • 0 comments

Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics | @cp-cancercell.bsky.social www.cell.com/cancer-cell/...

submitted 10 days ago • 0 comments

Fantastic review by Renato Ostuni and team on the conundrum how an inflammatory response can be immunosuppressive in #cancer IL-1β+ macrophages and the control of pathogenic inflammation in cancer | @cp-trendscancer.bsky.social www.cell.com/trends/immun...

submitted 11 days ago • 0 comments

Immunotherapy-related cognitive impairment after CAR T cell therapy in mice www.cell.com/cell/fulltex...

submitted 12 days ago • 0 comments

You can safely and effectively vaccinate against #COVID19 and seasonal #influenza at the same time, study shows jamanetwork.com/journals/jam...

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Tumor-draining lymph nodes – friend or foe during immune checkpoint therapy? | @cp-trendscancer.bsky.social www.sciencedirect.com/science/arti...

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The multilayered transcriptional architecture of glioblastoma ecosystems | Nature Genetics www.nature.com/articles/s41...

submitted 14 days ago • 0 comments

1/ When I started bioinformatics, I watched a postdoc type like a hacker in a movie. Lightning fast. No mouse. Just keys.

submitted 16 days ago • 1 comment

Data visualization is a critical step in data analysis. 8 links to bookmark for better data visualization:🧵

submitted 17 days ago • 1 comment

Hey, new paper by @cleggtom.bsky.social and me is just out in @pnas.org. This combines a lot of things that start with B: Biodiversity, Bipartite Networks, Bifurcations, Bacteria, ... www.pnas.org/doi/10.1073/... And yes, I know, Fig 1 looks like one of 'those' papers but please read on ...

submitted 17 days ago • 2 comments

Great and important work on macrophage replacement dynamics in the brai. And beyond. Congrats Kia and team! Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1 microglia: Immunity www.cell.com/immunity/ful...

submitted 18 days ago • 1 comment

Review @cp-immunity.bsky.social Role of specialized sensory neuron subtypes in modulating peripheral immune responses www.cell.com/immunity/ful...

submitted 19 days ago • 0 comments

Investigative needle core biopsies support multimodal deep-data generation in glioblastoma | Nature Communications www.nature.com/articles/s41...

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Microglial and TREM2 dialogues in the developing brain: Immunity www.cell.com/immunity/abs...

submitted 19 days ago • 0 comments

Border-associated macrophages as gatekeepers of brain homeostasis and immunity: Immunity www.cell.com/immunity/ful...

submitted 19 days ago • 0 comments

Niche-specific therapeutic targeting of myeloid cells in the central nervous system: Immunity | @cp-immunity.bsky.social www.cell.com/immunity/ful...

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Inflammasome signaling in astrocytes modulates hippocampal plasticity | @cp-immunity.bsky.social www.cell.com/immunity/ful...

submitted 21 days ago • 0 comments

For all the occasions you can’t relive on common sense. Here’s a guide on scientific image editing The do’s and don’ts of scientific image editing www.nature.com/articles/d41...

submitted 24 days ago • 0 comments

Perivascular macrophages in the central nervous system: insights into their roles in health and disease | Cell Death www.nature.com/articles/s41...

submitted 25 days ago • 0 comments

Yep - this review on brain #macrophages is definitely worth every minute of your time. Indulge and learn Central Nervous System Macrophages in Health and Disease | Annual Reviews www.annualreviews.org/content/jour...

submitted 28 days ago • 0 comments

Reducing the risk of all-cause dementia with intensive blood pressure control, the results of a cluster randomized trial in~34,000 participants. @naturemedicine.bsky.social www.nature.com/articles/s41...

submitted 33 days ago • 7 comments

Carl Sagan explains how the ancient Greeks knew the Earth was round and calculated its circumference over 2,000 years ago.

submitted 34 days ago • 409 comments

Massive multimodal analysis across #brain #tumor entities. Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence | bioRxiv www.biorxiv.org/content/10.1...

submitted 33 days ago • 0 comments

Whenever you want to convert almost any file format into markdown: this new tool will help you. Why bother? Markdown is the native language of #chatGPT github.com/microsoft/ma...

submitted 34 days ago • 0 comments

I’m a big fan of the @nejm.org illustrated glossary. See below how to genome instability is explained #cancer #scienceCommunication

submitted 35 days ago • 0 comments

New tools! GreenPy and ApplePy are fluorescent biosensors for pyruvate with huge responses (20–40x in vitro) and a range of affinities (10s of μM to mM). These should be game changers for imaging of metabolism! Great work by Shosei Imai @sikmys.bsky.social and team 👏. www.biorxiv.org/content/10.1...

submitted 35 days ago • 1 comment

Age-related meningeal extracellular matrix remodeling compromises CNS lymphatic function jneuroinflammation.biomedcentral.com/articles/10....

submitted 36 days ago • 0 comments

No matter how you turn these #maternal #mortality statistics it’s devastating for the richest county on earth www.axios.com/2025/02/06/b...

submitted 36 days ago • 0 comments

Are you interested in machine learning applications for single-cell genomics but don’t know where to get started? Check out our ML primer by the talented authors @nbinder1.bsky.social and Ashkan Khavaran www.frontiersin.org/journals/bio...

submitted 37 days ago • 0 comments

Utilize AI to generate high quality summaries of a research topic with references and limited hallucination. By @stanforduniversity.bsky.social storm.genie.stanford.edu

submitted 40 days ago • 0 comments

Fascinating: microglia(-like) cells can be found in the peripheral nervous system if you know where to look Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution | @cp-cell.bsky.social www.cell.com/cell/abstrac...

submitted 46 days ago • 0 comments

A comparative transcriptomic analysis of mouse demyelination models and Multiple Sclerosis lesions | @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

submitted 56 days ago • 0 comments

Transcriptomics in the era of long-read sequencing www.nature.com/articles/s41...

submitted 57 days ago • 1 comment

SpatialRNA: a Python package for easy application of Graph Neural Network models on single-molecule spatial transcriptomics dataset | @biorxivpreprint.bsky.social #paper www.biorxiv.org/content/10.1...

submitted 61 days ago • 0 comments

Single-cell spatial transcriptomic atlas of the whole mouse brain | @cellpress.bsky.social #paper www.cell.com/neuron/fullt...

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I can’t believe how sleek these plots look: Tidyplots empowers life scientists with easy code-based data visualization onlinelibrary.wiley.com/doi/10.1002/...

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Exploring and mitigating shortcomings in single-cell differential expression analysis with a new statistical paradigm genomebiology.biomedcentral.com/articles/10....

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The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis www.science.org/doi/10.1126/...

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MUUMI: an R package for statistical and network-based meta-analysis for MUlti-omics data Integration | @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

submitted 67 days ago • 0 comments

Integrating model systems and genomic insights to decipher mechanisms of cancer metastasis www.nature.com/articles/s41...

submitted 68 days ago • 0 comments

Social disadvantage accelerates aging | @naturemedicine.bsky.social www.nature.com/articles/s41...

submitted 70 days ago • 0 comments