Profile avatar
ryanhisner.bsky.social
Teacher. Learner. Investigating mysteries of SARS-CoV-2 evolution.
420 posts 7,968 followers 217 following
Regular Contributor
Active Commenter
Posts 10 Comments 40

Unreal. Free speech is dead in the USA.

submitted 3 days ago • 0 comments

Sooo happy to finally have this one published!! (3 years in the making… 👀) A comprehensive investigation into the recency and geographical origins of both SARS-CoVs that spilled to humans in the past few decades, now in @cp-cell.bsky.social www.cell.com/cell/fulltex...

submitted 5 days ago • 2 comments

Public Service Announcement: Tyler Starr is on Bluesky @tylernstarr.bsky.social‬ Thought everyone in the Covid/virology space should know. I didn't realize this until it was pointed out to me by @flodebarre.bsky.social, even though I'd previously searched for him.

submitted 6 days ago • 0 comments

He doesn’t deal with individual grants himself. So ironic then that one of touch stone lies spun by COVID conspiracists and the MAGA faithful is that Tony Fauci *personally* paid off Kristian Andersen and Bob Garry for changing their minds on virus origins with a CREID grant.

submitted 9 days ago • 2 comments

Update: Unexpectedly, this 50-spike-mutation sequence has transmitted to at least 1 other person. Most Canadian seqs seems to be from nursing homes, so this may be confined to one facility—something we've seen before. But it proves this is transmissible & perhaps capable of spreading more widely.

submitted 9 days ago • 4 comments

Lots of recombinants these days, but it's rare to see one involving BA.1. But a BA.1.17/KP.3.1.1 recombinant showed up today. Clean breakpoint near the end of ORF1a. Has ~25 private AA mutations in the BA.1.17-inherited ORF1a—many classic chronic-infection mutations—but only a few elsewhere. 1/4

submitted 9 days ago • 4 comments

Amidst the discussion of measles reestablishment in the US, the risk of rubella provides an instructive example of long-term delayed consequences that could resonate for decades ... or be stopped by coming to our senses 1/

submitted 11 days ago • 9 comments

Incredible how quickly Yunlong Cao & co provide us w/info on the latest emerging SARS-CoV-2 variants. Already, we have great data on BA.3.2 (the divergent saltation lineage detected in South Africa & the Netherlands & NB.1.8.1, an emerging contender for global dominance. 1/9

submitted 13 days ago • 5 comments

Great paper exploring a key aspect of the vitally important SARS-CoV-2 nucleocapsid protein. I don't think most people realize that Delta really consisted of several major lineages. One came to dominate, and it was probably entirely due to the key N mutation discussed here.

submitted 16 days ago • 2 comments

Long-term cohabitation with pathogenic viruses: generally a bad thing, even when mostly dormant.

submitted 16 days ago • 0 comments