samyers-lab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification. buff.ly/31NkUE7

submitted 3 days ago • 0 comments

Base editing 🥰😍🥰

submitted 4 days ago • 0 comments

Whoaaaaa

submitted 6 days ago • 0 comments

Welcome to the club

submitted 37 days ago • 0 comments

I don't love seeing that.

submitted 38 days ago • 0 comments

OGT touches many aspects of cell and molecular biology. We show that OGT restrains the DNA demethylation activity of the TETs, and guards against the reactivation of repressed endogenous retroviruses. www.nature.com/articles/s41... @faulknerlab.bsky.social @biomodal.bsky.social @lji.org #glycotime

submitted 38 days ago • 0 comments

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

submitted 39 days ago • 12 comments

Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.

submitted 40 days ago • 6 comments

With Butovsky Lab, we show that silencing TIM-3 in brain-resident immune cells prevents neurodegeneration in a mouse model of #Alzheimer’s disease. Deletion of TIM-3 in microglia enhance phagocytic clearance of toxic amyloid beta. #Immunosky🧪 www.nature.com/articles/s41...

submitted 40 days ago • 1 comment

Senator Cory Booker on the economic value of the NIH and what we stand to lose with the Trump administration destroying scientific research

submitted 48 days ago • 2 comments

Our study with Anjana Rao's lab was just published at NSMB 🥳 Shows how OGT prevents TET proteins from activating retrotransposons, particularly those in heterochromatin. Paper has 6-base and ONT sequencing data from OGT iKO mESCs, and also interesting OGT inhibitor data 👀. rdcu.be/efuho

submitted 53 days ago • 0 comments

"A GO term analysis? how is this helpful?"

submitted 53 days ago • 2 comments

Check out this great study by the Kronenberg lab on Fatty acid metabolism immunity nexus (FAMIN) aka LACC1 in T cells impacting IBD! www.nature.com/articles/s41...

submitted 63 days ago • 0 comments

@nytimes.com

submitted 72 days ago • 0 comments

Science rally @ucsandiego.bsky.social -- time for good trouble...

submitted 73 days ago • 2 comments

@talusbio.bsky.social is a finalist for the Health Innovation of the Year @geekwire.com award for our TF-Scan #TeamMassSpec-based #proteomics platform for #epigenetics #DrugDiscovery! The winner is picked by community voting, please vote for us through March 23rd! lnkd.in/gNi5MVeh 🧬🧪

submitted 73 days ago • 1 comment

Come on down, nerds.

submitted 73 days ago • 0 comments

See y'all at noon!

submitted 73 days ago • 0 comments

Today seemed like a good day to cancel my Amazon Prime subscription. Long overdue, especially with their delivery trucks constantly blocking side walks, bike lanes, bus stops. Makes it hard for local businesses to compete when we let them operate with so many negative externalities for free!

submitted 81 days ago • 0 comments

STAND UP FOR SCIENCE! Join us and thousands nationwide on Friday, March 7th at noon at the UC San Diego Geisel Library / Silent Tree

submitted 81 days ago • 0 comments

We have great speakers at our @lji.org seminar series. Come join!

submitted 84 days ago • 0 comments

Come join the Inaugural LEAD day lectureship @lji.org, sponsored by the Global Autoimmune Institute

submitted 85 days ago • 0 comments

A divergent color scale on sequential data is even more reason we need to train the next gen of scientists. Blue to red is a little on the nose too. Anyway, all states will struggle regardless. Contact your representatives.

submitted 98 days ago • 0 comments

if you happen to live in a state represented by someone on the senate HELP committee, PLEASE call your senators and tell them how this will affect science (and employment) in your state! explain things to your family and friends and get them to call too!

submitted 101 days ago • 0 comments

This is a list of blockbuster drugs in 2024. Guess how many can trace their origins to NIH funded research? All of them.

submitted 101 days ago • 10 comments

15%. In 2018, 10% was tried, but it was blocked by Congress. www.nytimes.com/2017/09/11/u... www.science.org/content/arti...

submitted 101 days ago • 9 comments

I hear your frustration. Remember, this place is an echo chamber - get out and yell it to the world @cnn.com @npr.org @foxnewscorporation.bsky.social - The new NIH policy cannot pass.

submitted 101 days ago • 0 comments

Oh. My. God. grants.nih.gov/grants/guide...

submitted 101 days ago • 19 comments

Truncated gRNA sequences to target Cas9 fusions to hundreds of sites with similar sequences: www.nature.com/articles/s41... This should address a question I commonly get for GLoPro (PMID: 29735997), about targeting TF binding sites throughout the genome, rather than a single locus. Cool work.

submitted 102 days ago • 0 comments

My man @duckerlab.bsky.social the "diet researcher"

submitted 114 days ago • 0 comments

With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory.bsky.social @jzylicz.bsky.social @pasquelab.bsky.social and Nicolas Rivron. tinyurl.com/5n6z9rt9

submitted 119 days ago • 3 comments

The super-rich spend millions in attempts to extend their lives. Turns out you just need to jump on a bike. www.forbes.com/sites/carlto...

submitted 130 days ago • 2 comments