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sleemmz.bsky.social
Assistant Professor, Tish Cancer Institute @Mount Sinai. Colorectal Cancer. Oncofetal reprogramming. Views are my own. "By land and by sea, Carthage will rise again" https://profiles.mountsinai.org/slim-mzoughi
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🔈We've got the cover of the 2nd NG issue for 2025🙌 Read about the cover: In the comment👇 Also check out our research briefing🚨 (link below): nature.com/articles/s41... nature.com/articles/s41...

📢ONLINE @naturegenet.bsky.social 📰Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer. By @sleemmz.bsky.social, @guccionelab.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...

Nice paper from @sleemmz.bsky.social et al underscoring the importance of stem cell transdetermination in CRC. RXR, YAP, and AP1 signalling collectively control access to revival stem cells and inhibition of these nodes limits plasticity to improve chemosensitivity. www.nature.com/articles/s41...

So happy to see this live, Slim! Congratulations to you, Ernesto and the whole team for your resilience, vision and creativity!

Out now @naturegenet.bsky.social: **Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer** www.nature.com/articles/s41... Interesting story about #oncofetal #reprogramming and phenotypic #plasticity in #colorectal #cancer. #science #epigenetics #OncoSky

Thrilled to share my 1st brainchild, out today @naturegenet.bsky.social 🚀 Been hearing a lot about fetal-like states lately? We uncover the molecular mechanisms, functional significance and clinical relevance of #oncofetal reprogramming in CRC. www.nature.com/articles/s41... (rdcu.be/d9iSN) a 🧵

The Human Cell Atlas is yielding detailed maps of human tissues and systems throughout life, along with methods to handle single-cell data. Four scientists reflect in Nature on how the project is transforming our understanding of human biology. 🧪

A shared meal, a kiss on the cheek: these social acts bring people together — and bring their microbiomes together, too. …. It is fascinating how our microbiome is shaped! www.nature.com/articles/d41...

go.bsky.app/QW8Ghu5

Happy with the move to🦋 ! I hope we can use this platform as a fresh start to foster meaningful scientific discussions and collegiality, rather than superficial praise or unproductive disagreements.