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thomaslecuit.bsky.social
How are biological forms encoded? Group leader at IBDM Marseille, director of Turing Center for living systems (CENTURI). Professor at Collège de France, Paris: Dynamics of living systems
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Prolific Poster

New preprint from the lab! 👇

Second preprint from the lab in a week! This time led by Aurelien. Combining live imaging, quantitative image analysis and perturbations, he clarifies the mechanisms leading to primitive induction. 👇

Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision www.biorxiv.org/content/10.1...

Experimental embryology postdoc available in my lab at the @biology.ox.ac.uk @ox.ac.uk working on the evolution of vertebral counts. Reach out if you’re passionate about EvoDevo, enjoy lab work and microscopy and are into or could get into cichlid fishes. Deadline on the 16th June. Please share!

www.geekwire.com/2025/seattle...

It was also a very good time for discussions in nice restaurants and bars 😊

The symposium at the College de France yesterday on Biological information was wonderful. High level presentations and discussions among speakers and participants. Videos will be online soon!🤩 Huge thanks to the speakers 🙏🏼🙏🏼

Our field has lost an amazing scientist, mentor, and old friend. Benny, along with Mike Hoffman, had a brilliant idea in the early 1980s. The first oncogenes were being cloned and they realized if we wanted to understand their roles in cancer, we needed to understand their normal function 1/n 🧪

Please RT. If you are in Paris, see announcement of 4 lectures by @stephenquake.bsky.social at @collegedefrance.bsky.social on « Understanding the mysteries of the cell », hosted by colleagues Edith Heard, Hugues de Thé and myself. The 1st two will be on 12 and 26 May, all info below. See you there!

🟣 L’Administrateur, l’Assemblée des professeurs et toute la communauté du Collège de France apprennent avec une profonde tristesse le décès de Xavier Le Pichon, professeur émérite du Collège de France, titulaire de la chaire de #Géodynamique (1986-2008).

⭐️ Please Fwd. Are you in Paris on 16th May? See👇 poster of symposium on « Information processing in biological systems » @collegedefrance.bsky.social Fantastic line of speakers 🤩. It is free, w/o registration, and it will be exciting.m! Follows from my series of lectures at CdF last fall.

Shocking: a pioneer in quantitative developmental biology passed... one of my all-time heroes! He had a dominant influence on many in the early 2000s when this field started to take off. What a loss! Obituary written by two of his former students: biologicalsciences.uchicago.edu/news/john-re...

Happy hour @centuri-ls.bsky.social attracted a lot of us today…! 🤩

🔔🧪 I'm deeply saddened by the passing of Michael Sheetz, a true pioneer in #mechanobiology. I'll always cherish our lovely times in NYC, Singapore, Zurich, and Sydney. My heartfelt condolences to his family and friends in this difficult time. So long, Mike 🥺😔

@academiesciences.bsky.social Une bonne occasion de prendre la parole…!

📣Exciting meeting ahead! Join us next June in beautiful Cassis for #ShapingLife3! www.atoutcom.com/shaping-life/ @justinmcrocker.bsky.social @mhverlhac.bsky.social @guignardlab.bsky.social @bulutkarslioglu.bsky.social @dudinlab.bsky.social @flowerwhatelse.bsky.social @sfbd.bsky.social

New research into the single-celled organism is providing clues about what the early planet looked like – and raising the prospect that we may not be alone in the universe! source: @philipcball.bsky.social @theguardian.com www.theguardian.com/science/2025...

Great to spend time with Claude Desplan from NYU… 😁in whose lab I discovered the joy of science 32 years ago 😬, when I was the same age as the students in the class!

We went with students from NYU Abu Dhabi and NY to the sand dunes. An amazing experience 🤩. We heard to sounds of dunes as we went down.

We had an amazing seminar from photographer Yousef Al Abshi (www.uaemacro.com), in the lineage of Robert Hooke’s Micrographia. The best ever macro photographies of insects I have ever seen. Art and science at its best 🤩

This morning was getting prepared to foldscope in the Mangrove next week. Students immediately picked up on this and started their own investigation. Next time, @prakashlab.bsky.social you come to spread this further around!

After the sun had set we were searched for traces of life with torches

Our first expedition to the desert to look for snakes, scorpions and more was an amazing experience. Guided by terrific Theo Busschau from South Africa, PhD student at NYUAD, a professional guide, and snakes lover.

Very much enjoying being at NYU Abu Dhabi for 2 weeks to teach undergraduate students a class called “The puzzles of life”. Combines classes, seminars, lab activity and field expeditions. A very rich and intense experience for students coming from various corners of the world, and for me 🤩

CallelongueForEver

Move over mitochondria, a new organelle called the nitroplast is here. In a Science study from earlier this year, researchers report that a nitrogen-fixing organelle has been identified in a marine alga. Learn more in this #SciencePerspective:

Lumières de Noël depuis Notre Dame de la Garde!

We have a new opening! Amazing environment colleagues and facility! Join us!

The CENTURI PhD program is now accepting applications! 📢 If you are interested in joining an interdisciplinary research community, submit your complete application by January 20, 2024. For more details, visit: centuri-livingsystems.org/recruitment/ #PhD #PhDOpportunities #CENTURI

Here is the link to last course @collegedefrance.bsky.social on biological information, devoted to cellular learning & memory. From molecular memory (allostery, protein modification) to signalling networks with memory (bistability etc),structural memory & cell memory. Enjoy! tinyurl.com/n4hfx4ec

Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...

Building a capacity for making Turing patterns into bacteria. This is very cool. www.cell.com/cell-systems...

What if plate tectonics had something to do with development? We found a new framework for dynamic origami in tissue folding in a nerveless animal. Will share thread; but if you are at #cellbio2024, see @cbrannon.bsky.social poster B399 today. Not at ASCB; read www.biorxiv.org/content/10.1...

Infamous paper that popularized unproven COVID-19 treatment finally retracted Study on hydroxychloroquine by Didier Raoult and colleagues gets pulled on ethical and scientific grounds @cathleenogrady.bsky.social reports. www.science.org/content/arti...

Great time after last course @collegedefrance.bsky.social today in company of Aleks Walczak, Vincent Hakim, François Schweisguth, Jacques Prost and Pierre Sens 🤩. This series of courses on information was an amazing (&exhausting) experience. 16th May, Symposium at CdF on information processing.

Could stochasticity play a role in ensuring robustness during development? Read this 'Behind the paper' story from Bernat Corominas-Murtra about his work with Dimitri Fabreges, @virginieuhlmann.bsky.social, @ehannezo.bsky.social, Takashi Hiiragi @hubrechtinstitute.bsky.social & co: #DevBio

Breaking news : L'Académie des sciences accueille 18 nouveaux membres dès 2025, avec une majorité féminine pour la 1ère fois depuis 1666 👩‍🔬 : un symbole fort pour la parité en science ! 💥 🔗 En savoir plus sur les nouveaux membres : urlr.me/mntDHX

[NOUVELLE PRESIDENTE A L'ACADEMIE DES SCIENCES] Françoise Combes élue présidente pour 2025-2026. Elle succède à Alain Fischer et devient la 2e femme à présider cette illustre institution, après Marianne Grunberg-Manago. @combesfrancoise.bsky.social @collegedefrance.bsky.social

Happy to share ⬇️ link to pdf/video of lecture at College de France, on Structural & geometric information 🤩. An opportunity to broaden the concept of heredity beyond genomes. Tomorrow, last lecture of this year on Biological information, devoted to Memory and learning in cells. tinyurl.com/2y7hpu2r

Wonderful. And most powerful ending…

A few days left to apply 🙌🏻

Below: link to pdf/video of 4th lecture at College de France 😊: "Encoding, decoding and representations of Time". I discuss global & local tuning of biological timescales. Information decoded from dynamics can be quantified & is rich. Ex in vitro and in vivo. Enjoy! tinyurl.com/2n8n3s9u

CENTURI Call for PhD Project 2025 is open! For more details and eligibility criteria contact [email protected]

Glowing Paris yesterday night 🤩

A piece of history: the first science journal

The first session of our #CENTURIDAY chaired by @biancah0406.bsky.social is ending now with the talk of Alexandre Ortega, in @cirm-math.bsky.social

Where does pattern come from inside cells? in this revised preprint, @aralbright.bsky.social Shows that regionalization of mRNA in a Stentor cell depends on dynein motors and the microtubule cytoskeleton doi.org/10.1101/2023...

La vidéo de cette conférence est maintenant disponible @ www.bnf.fr/fr/agenda/le.... Avec une courte visite de quelques appartements du 11 rue Simon-Crubellier, dans le 17ème #puzzles @collegedefrance.bsky.social @genevunige.bsky.social

New @dev-journal.bsky.social editorial We know we have high standards - but we're committed to making publishing with us constructive From clear revision guidance to limitations sections & transparent peer review, we're here to help you share your science journals.biologists.com/dev/article/...