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timcoorens.bsky.social
Research Group Leader at EMBL-EBI | Former postdoc at Broad Institute | Former PhD student at Sanger Institute | Lineage tracing, cancer genomics, human development
25 posts 503 followers 135 following
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Social media grump Kamila has finally made it onto Bluesky! Please check out my new perspective on metastasis evolution in @natrevcancer.nature.com if you need a reprieve from the news. I tried my best to develop some new conceptual thoughts here, you be the judge whether I succeeded.

submitted 27 days ago • 0 comments

If you’ve ever wondered about the statistical significance of differences among mutational signature profiles, check out our new Aggregate Mutation Spectrum Distance (AMSD) preprint co-led by Sam Hart and @alisonfeder.bsky.social with @nalcala.bsky.social www.biorxiv.org/cgi/content/...

submitted 27 days ago • 1 comment

Keeping you in the loop! ➰ Our Linktree includes all SMaHT websites and social media accounts for easy and consistent access. Find all our social media accounts in one place: linktr.ee/smahtnetwork

submitted 31 days ago • 0 comments

Thrilled to see my #MITS25 talk brought to life by the brilliant 🎨 @atjcagan.bsky.social! Dive into the stellar science from @g-agarwal.bsky.social & co - fresh on bioRxiv: www.biorxiv.org/content/10.1... #Genomics #SomaticEvolution

submitted 46 days ago • 0 comments

The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our @nature.com paper: www.nature.com/articles/s41...

submitted 88 days ago • 3 comments

Excited to share our new preprint demonstrating somatic rescue mutations in a genetic liver disease! [1/12] www.nature.com/articles/s41...

submitted 96 days ago • 3 comments

@timcoorens.bsky.social diving into the Bostonian wing of the SMaHT program (a.k.a. 'wicked SMaHT), detailing new sequencing solution for ultra high accuracy duplex sequencing, essential for detecting somatic variation #AGBTgm

submitted 112 days ago • 0 comments

Awesome talk by @timcoorens.bsky.social on the detection and interpretation of somatic mutations. Now hiring postdocs! #AGBT25 | #AGBTGM

submitted 112 days ago • 0 comments

First large-scale analysis of chemical toxicity in primary human hepatocytes! www.biorxiv.org/content/10.1...

submitted 133 days ago • 1 comment

Building on our discovery of #LesionSegregation, @mikespencerchapman.bsky.social and colleagues from @sangerinstitute.bsky.social find that some DNA lesions can persist in humans for months or years! "Prolonged persistence of mutagenic DNA lesions in somatic cells" www.nature.com/articles/s41...

submitted 152 days ago • 1 comment

Our new perspective article describing the human and non-human primate developmental GTEx projects is now out in @nature.com! We outline the scope, vision, opportunities and challenges of these projects here: www.nature.com/articles/s41...

submitted 152 days ago • 1 comment

The abstract deadline for "Mutations in Time and Space 2025" is in a week! Please register here: broadinstitute.swoogo.com/mits2025

submitted 157 days ago • 0 comments

Spread the word! Registration for the "Mutations in Time and Space" conference is open. The meeting is all about the origins, patterns, and consequences of mutations across cells, individuals, populations, species. Abstract submission deadline is Jan 17th broadinstitute.swoogo.com/mits2025/597...

submitted 192 days ago • 1 comment

Let's build a starter pack for childhood cancer research. Please send a message to be added! 🎗️ go.bsky.app/Tpd9QnM

submitted 204 days ago • 30 comments