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Recent Findings in N6-Methyladenosine Modification and Significance in Pancreatic Cancer 🧪 onlinelibrary.wiley.com/doi/10.1002/...

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Inhibition of NAD-GPx4 axis and MEK triggers ferroptosis to suppress pancreatic ductal adenocarcinoma 🧪 www.sciencedirect.com/science/arti...

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Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis 🧪 www.biorxiv.org/content/10.1...

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Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in #PancreaticCancer 🧪 febs.onlinelibrary.wiley.com/doi/10.1002/...

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MLOmics: Cancer Multi-Omics Database for Machine Learning 🧪 🧬🖥️ www.nature.com/articles/s41...

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Galectin-3 in tumor-stromal cells enhances gemcitabine resistance in pancreatic adenocarcinoma by suppressing oxidative phosphorylation 🧪 www.sciencedirect.com/science/arti...

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The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets 🧪 www.sciencedirect.com/science/arti...

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Macrophage activation determines muscle wasting in #PancreaticCancer 🧪 www.nature.com/articles/s41...

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Disabling PSGL-1 abrogates immune suppression and resistance to PD-1 blockade in pancreatic cancer 🧪 www.biorxiv.org/content/10.1...

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Immune stromal components impede biological effectiveness of carbon ion therapy in a preclinical model of pancreatic ductal adenocarcinoma 🧪 www.biorxiv.org/content/10.1...

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Spatial Biology and Organoid Technologies Reveal a Potential Therapy-Resistant Cancer Stem Cell Population in Pancreatic Ductal Adenocarcinoma 🧪 www.biorxiv.org/content/10.1...

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Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression 🧪 www.sciencedirect.com/science/arti...

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LINC00431 modulates KRAS and p53 stability to drive pancreatic cancer progression under hypoxia 🧪 www.sciencedirect.com/science/arti...

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Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA 🧪 www.nature.com/articles/s41...

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Sharma et al., «Integrating AI/ML and multi-omics approaches to investigate the role of TNFRSF10A/TRAILR1 and its potential targets in pancreatic cancer». 🧪🧬🖥️ www.sciencedirect.com/science/arti...

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An antibody-drug conjugate targeting soluble and membrane-bound TGFα is effective against pancreatic tumors 🧪 jeccr.biomedcentral.com/articles/10....

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Just a nice reminder! 🧪🧬🖥️ I found this GitHub very useful: github.com/cxli233/Frie...

submitted 8 days ago • 2 comments

It’s been a real pleasure having Giorgio Valentini in the lab these past weeks. Great scientific discussions, sharp insights, and valuable feedback. Thank you, Giorgio—come back soon! #AcademicSky #bioinformatics #collaboration

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JOB ALERT!! 🧪 We are offering a postdoc position within our “antiCAFing” ERC-CoG project to investigate the interplay CAFs:endothelial cells and its impact in aberrant vascularization in tumors. More details below 👇. Please spread the word.

submitted 9 days ago • 1 comment

Mutational and expression analysis of classical protein tyrosine phosphatase genes in pancreatic ductal adenocarcinoma 🧪🧬🖥️ www.sciencedirect.com/science/arti...

submitted 10 days ago • 0 comments

Paricalcitol plus hydroxychloroquine enhances gemcitabine activity and induces mesenchymal to epithelial transition in pancreatic ductal adenocarcinoma: A single cell RNA-seq analysis 🧪 www.sciencedirect.com/science/arti...

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Genomic instability, DNA damage response and telomere homeostasis in pancreatic cancer 🧪 www.sciencedirect.com/science/arti...

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It has been a real pleasure to present our results at Hospital Puerta de Hierro. Great to go back where I did my Ph.D. and reconnect with old friends! @ufvmadrid.bsky.social

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🎓 Curso de Verano UFV: “Cáncer de Páncreas: De la Clínica al Laboratorio” 📅 24-28 junio | 📍 Madrid 🧬 Investigación, clínica, pacientes y ciencia real Dirigido a estudiantes de biomedicina, medicina y más 🔗 www.ufv.es/curso-de-ver... #oncología #PDAC @aseica.bsky.social @ufvmadrid.bsky.social

submitted 11 days ago • 1 comment

Novel Cyano-Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in #PancreaticCancer Treatment 🧪 advanced.onlinelibrary.wiley.com/doi/10.1002/...

submitted 12 days ago • 0 comments

¡Abierta la preinscripción del Máster en Bioinformática y Ciencias de Datos en Medicina Personalizada de Precisión y Salud 2025/26! 📍Organizan: @saludisciii.bsky.social @cniostopcancer.bsky.social @bsc-cns.bsky.social 🤝 Colaboran: SEBiot,Instituto Roche 📅 Plazas limitadas 🔗 masterbioinformatica.com

submitted 21 days ago • 0 comments

Novel Pt@PCN-Cu-induced cuproptosis amplifies αPD-L1 immunotherapy in pancreatic ductal adenocarcinoma through mitochondrial HK2-mediated PD-L1 upregulation 🧪 jeccr.biomedcentral.com/articles/10....

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Phosphorylation of USP32 by CDK5 regulates Rap1 stability and therapeutic resistance in pancreatic ductal adenocarcinoma 🧪 #PancreaticCancer www.nature.com/articles/s41...

submitted 15 days ago • 0 comments

Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma 🧪 #PancreaticCancer www.nature.com/articles/s41...

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PRMT5 Promotes #PancreaticCancer Tumorigenesis via Positive PRMT5/C-Myc Feedback Loop 🧪 onlinelibrary.wiley.com/doi/10.1002/...

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Evaluating the factors influencing accuracy, interpretability, and reproducibility in the use of machine learning classifiers in biology to enable standardization 🧬🖥️ www.nature.com/articles/s41...

submitted 19 days ago • 0 comments

A PP2A-mtATR-tBid axis links DNA damage-induced CIP2A degradation to apoptotic dormancy and therapeutic resistance in PDAC 🧪 #PancreaticCancer www.sciencedirect.com/science/arti...

submitted 21 days ago • 0 comments

The Aging Microenvironment as a Determinant of Immune Exclusion and Metastatic Fate in #PancreaticCancer 🧪 www.biorxiv.org/content/10.1...

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Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition 🧪 #PancreaticCancer www.science.org/doi/10.1126/...

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It was a pleasure to present our recent results at VHIR. Many thanks to Juan Ángel Recio for his kind invitation. The new VHIR institute is truly impressive! @vhir.bsky.social @ufvmadrid.bsky.social #AcademicSky

submitted 25 days ago • 0 comments

Oncogenic proteome of #PancreaticCancer extracellular vesicles: sodium/myo-inositol cotransporter as a potential marker 🧪 www.nature.com/articles/s41...

submitted 26 days ago • 0 comments

Deep scSTAR: leveraging deep learning for the extraction and enhancement of phenotype-associated features from single-cell RNA sequencing and spatial transcriptomics data 🧬🖥️ academic.oup.com/bib/article/...

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High-Sensitive Spatial Proteomics for Pancreatic Cancer Progression Analysis 🧪🧬🖥️ www.biorxiv.org/content/10.1...

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NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress 🧪 #PancreaticCancer www.biorxiv.org/content/10.1...

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Molecular landscape of endometrioid Cancer: Integrating multiomics and deep learning for personalized survival prediction 🧬🖥️ www.sciencedirect.com/science/arti...

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Clinicopathological and molecular characterization of KRAS wild-type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes #PancreaticCancer 🧪 pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/...

submitted 28 days ago • 0 comments

SpaNorm: spatially-aware normalization for spatial transcriptomics data 🧬🖥️ genomebiology.biomedcentral.com/articles/10....

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Benchmarking algorithms for spatially variable gene identification in spatial transcriptomics 🧬🖥️ academic.oup.com/bioinformati...

submitted 32 days ago • 0 comments