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zhenggang.bsky.social
Sanford Fellow @UCSDCompassion Alumni @HHMI, Identifying 🧬 for self/social motivation with 3D spatial omics
15 posts 55 followers 328 following
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Excited to share that the astrocyte-centered half of my thesis work is now out @science.org ! With @mishaahrens.bsky.social and @marcduque.bsky.social science.org/doi/10.1126/... 1/8

submitted 19 days ago • 5 comments

Thrilled to share our work in ScienceAdvances: “Chronic ethanol exposure produces sex-dependent impairments in value computations in the striatum.” Huge thanks to Tricia @janaklab.bsky.social, Daeyeol @ungteoriz.bsky.social, Angela, and my friend Robin! www.science.org/doi/full/10....

submitted 63 days ago • 1 comment

Many of us use 2p scopes to image 3D volumes of brain. But then we analyze the data plane by plane, resulting in duplicated neurons, missed neurons, and low s/n. Let's go 3D! Suite3D: Volumetric cell detection for two-photon microscopy by @haydari.bsky.social & team. www.biorxiv.org/content/10.1...

submitted 64 days ago • 0 comments

(1/n) Why is it so hard to stop eating when something tastes amazing? Our new @ science.org paper reveals that dopamine helps sustain our drive for tasty treats—and may explain how anti-obesity Ozempic tames those urges. doi.org/10.1126/science.adt0773

submitted 66 days ago • 2 comments

New @science.org Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss www.science.org/doi/10.1126/...

submitted 69 days ago • 11 comments

Our paper from Junchol Park and collaborators that has been brewing for a while. Trying to capture our thinking about what action specification in striatum means and what would constitute evidence for such a model. Longer thread soon, but it’s online now. www.cell.com/neuron/fullt...

submitted 132 days ago • 1 comment

HCN1 channels in GABAergic amygdalar neurons underpin male-biased aggressive behaviors https://www.biorxiv.org/content/10.1101/2024.12.07.627305v1

submitted 178 days ago • 0 comments