Beautiful paper on mitochondrial DNA (mtDNA) stress sensing, from our postdoc Alva Sainz @signscaztl.bsky.social of her Ph.D work in the Shadel lab!
Reposted from Journal of Cell Biology
New: Sainz, Shadel et al. @salkinstitute.bsky.social investigate mitochondrial respiration-independent signaling induced by acute mtDNA depletion and uncover a role for FAM43A in a CHK2-dependent mitochondrial stress signaling pathway. https://buff.ly/40MBmIW
#mitochondria

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