👇 Did you know one can use pulsed lasers not only to increase contrast in #cryoEM images, but also to reduce preferred particle orientation, by melting & re-vitrifying samples in a controlled way? ❄️🔬
Reposted from cryoEM papers
Laser Flash Melting Cryo-EM Samples to Overcome Preferred Orientation biorxiv.org/cgi/content/short/2024.11.21.624652v1

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