Banger of a #LongCovid paper in pre-print today showing that replicating viral DNA can persist in hamsters at least 80 days after intranasal infection. The study team were able to isolate and amplify infectious virus in 84% of experimental animals. www.biorxiv.org/content/10.1... 1/ - ThreadSky

putrinolab.bsky.social • 161 days ago

Banger of a #LongCovid paper in pre-print today showing that replicating viral DNA can persist in hamsters at least 80 days after intranasal infection.

The study team were able to isolate and amplify infectious virus in 84% of experimental animals.

https://www.biorxiv.org/content/10.1101/2024.12.16.628627v1.full.pdf

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madamequisairtout.bsky.social•160 days ago

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yeahnaa333.bsky.social•161 days ago

Viral DNA? …or you mean RNA?

unrealarthur.bsky.social•157 days ago

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marcusfitzsimons.bsky.social•160 days ago

bit naughty of me, but try convincing Marc V! he says we're as bad as #AntiVaxxers for believing covid is harmful.

johnhatchard.bsky.social•158 days ago

Two new studies paint a comprehensive picture of current long COVID U.S. cases.

Both suggest the condition limits daily activities for a significant proportion of those affected ...

putrinolab.bsky.social•161 days ago

This is really interesting data that, once again, provides rationale and paves the way for the need for more antiviral and monoclonal trials (and combination antiviral + monoclonal trials!). For those following the actual persistence data this is just one more study confirming 2/

putrinolab.bsky.social•161 days ago

what we already knew, but it sure is nice to keep a running tally of studies that show persistence of *replicating* viral RNA. For the deniers: I’m delighted to inform you that your job just got a little harder. Every day we learn more about the reality of pathogen persistence 3/

putrinolab.bsky.social•161 days ago

and it’s role in driving many of the symptoms associated with #LongCOVID and other infection-associated chronic conditions. Are persistent pathogens the whole picture? Definitely not (especially for those who have been sick for a while), but it is a crucial piece of the puzzle 4/

johnhatchard.bsky.social•158 days ago

Two new studies paint a comprehensive picture of current long COVID U.S. cases.

Both suggest the condition limits daily activities for a significant proportion of those affected ...

putrinolab.bsky.social•161 days ago

and continuing to ignore it is no longer practical or consistent with the consensus science. SARS-CoV-2 persistence is a fact of #LongCOVID pathobiology. Denying it is fringe. Have a great day ✌🏼 /end

kateviolette.com•161 days ago

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