Too much protein in the diet may carry a risk of heart disease secondary to leucine's effect. An important report considering recent advocacy for very high-protein diets.
https://www.nature.com/articles/s42255-024-00984-2
https://www.nature.com/articles/s42255-024-00984-2
Comments
If I understood it correctly leucine level should remain under this threshold and exercise helps in lowering it's level. So only with an active life-style it's safe to increase, also, protein intakes