Suppression of the inflammation that occurs with aging ("inflammaging") by blocking thrombospondin-1 (Thbs1), prevented age-related blood stem cell defects and expanded lifespan in the mouse model (KO-knockout)
https://www.science.org/doi/10.1126/sciimmunol.ads1556
https://www.science.org/doi/10.1126/sciimmunol.ads1556
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(do not take mega-doses of VitaminD, 4000iu daily max unless you test deficient)