Altogether, proximity is key and search normally stays around the DSB. When it comes choosing a donor, only these sequences are candidates. - ThreadSky

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jcornlab.bsky.social • 46 days ago

Altogether, proximity is key and search normally stays around the DSB. When it comes choosing a donor, only these sequences are candidates.

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jcornlab.bsky.social•46 days ago

This project was driven by amazing graduate student https://charlesyeh.bsky.social, with lots of amazing collaborators over the years.

jcornlab.bsky.social•46 days ago

Curious about how cohesin guides homology search via loops & sister chromatid linkages? Check out this new preprint by https://fedeteloni.bsky.social & https://gerlichlab.bsky.social! 👉 https://tinyurl.com/DSBcohesin

jcornlab.bsky.social•46 days ago

If you’re interested in how loop-extruding cohesin drives the homology search during HR, check out also this new preprint from https://albertomarin.bsky.social in the Taekjip Ha lab (https://doi.org/10.1101/2025.02.10.637451)

jcornlab.bsky.social•46 days ago

I’m still learning Bluesky, so now tagging people I mis-tagged. Sorry! @charlesyeh.bsky.social @albertomarin.bsky.social @fedeteloni.bsky.social @gerlichlab.bsky.social

docdellaire.bsky.social•45 days ago

Congrats very cool! - I have a patent and a paper on 3D homology search mapping (Recombination Access Mapping) that would make an excellent citation of prior work in this area see: https://pmc.ncbi.nlm.nih.gov/articles/PMC232405/ patent here: https://patents.google.com/patent/US6342354B1/en?inventor=Graham+Dellaire&oq=Graham+Dellaire+

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