Great explainer. "Michigan estimates that the proposed change in NIH funding would create a $181 million annual hole in its budget." <-- huge number and at $2.46 in economic activity for every $1 of funding, up to a $4.428 million loss, in Michigan alone.

https://www.nih.gov/about-nih/what-we-do/impact-nih-research/serving-society/direct-economic-contributions#:~:text=Each%20year%2C%20NIH%20awards%20over,approximately%20%242.46%20of%20economic%20activity