Could maybe have been worded better if it was about measuring those metrics during another bout of exercise. - ThreadSky

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dimapodolsky.bsky.social • 22 days ago

Could maybe have been worded better if it was about measuring those metrics during another bout of exercise.

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Also, has blood oxygen been tested before Keller 2024 in a 2 day CPET? Glancing at other studies, I don't see it mentioned.

exceedhergrasp1.bsky.social•22 days ago

Not at rest, during exercise.

exceedhergrasp1.bsky.social•22 days ago

If generally you have questions on this, I'd recommend looking up 2-day CPET on me-pedia

dimapodolsky.bsky.social•22 days ago

Ah I see Vermeulen 2010 showed this difference, but several of the papers with a "calculated" SpO2 in the mepedia table dont actually report anything in the text about it (e.g. Hodges, Davenport, Nelson, van Campen) so hard to say if it was different from controls. 1/

dimapodolsky.bsky.social•22 days ago

As far as I can tell only two studies have shown SpO2 decreases more in MECFS than controls, and at least four studies that apparently had that data but didnt report it, which makes me think the difference wasn't replicated in those studies.

exceedhergrasp1.bsky.social•22 days ago

VO2 drops-- it's one of the most repeated findings

dimapodolsky.bsky.social•22 days ago

(I assume the other studies I mentioned tested SpO2 and put it in supplementary files, otherwise I'm not sure what the MEpedia calculated figures are based on. And AFAICT the figures in the table are not compared to controls anyway.)

dimapodolsky.bsky.social•22 days ago

* both are in figure 3.

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