{ukbrapR} (phonetically: ‘U-K-B-wrapper’) makes UK Biobank cloud platform (RAP) analysis quicker, easier, and more reproducible
In particular, for a given list of diagnostic codes it is trivially easy to ascertain diagnoses from any source (HES, GP, death, cancer, etc)
https://lcpilling.github.io/ukbrapR/
In particular, for a given list of diagnostic codes it is trivially easy to ascertain diagnoses from any source (HES, GP, death, cancer, etc)
https://lcpilling.github.io/ukbrapR/
Comments
- Trivially easy PheWAS analysis with tidy model output
- Quick functions for data manipulation and working with test statistics
https://lcpilling.github.io/lukesRlib/
1. identify loci either distance-based identification, or LD pruning (can use local Plink and reference data)
2. identify nearest gene for given SNP list (e.g., loci from 1)
https://lcpilling.github.io/gwasRtools/
TWIST (Triangulation WIthin A STudy) estimates the ‘genetically moderated treatment effect’ - the excess disease or outcomes in individuals prescribed a specific medication that are attributed to genetic variant(s)
https://lcpilling.github.io/twistR/