POET group from 🇩🇰
➡️ Following the POET trial, ⬇️ in median LOS 🏥 of 8 days with no change in mortality & an associated ⬇️ rate of relapse of bacteremia
#IDsky #Medsky 🧵
(1/5)
➡️ Following the POET trial, ⬇️ in median LOS 🏥 of 8 days with no change in mortality & an associated ⬇️ rate of relapse of bacteremia
#IDsky #Medsky 🧵
(1/5)
Comments
-Dr Brad Spellberg
- @drtoddlee.bsky.social
- @absteward.bsky.social
- @dremilymcd.bsky.social
Endocarditis ❤️ Therapy
➡️ The Move From Expert Opinion to Evidence
(2/5)
Trop cool!
least as effective as IV only therapy for endocarditis is settled based on an overwhelming concordance of DATA»
(3/5)
🖖 «... to paraphrase Mr Spock from the movie Star Trek VI: The Undiscovered Country, “[POET] is the beginning of wisdom; not the end.”»
POET + 3 RCTs + a quasi-exp pre/post + observational studies
➡️ Data 🚫 support predetermined # IV lead before oral
(4/5)
1) hemodynamic stability
2) source control completed / cleared bacteremia
3) patient’s intestine OK for oral
4) oral regimen published efficacy vs pathogen
5) no psychosocial or $ reasons to prefer IV
(5/5)
(p.s. I can share the editorial if you DM 🤫)
⬇️ #IDsky
https://bsky.app/profile/absteward.bsky.social/post/3lbrwsczh7c26