Hearing a lot about inadequate prepress and print design classes, so here's a link to the comic by me and @daisyfm.net about best practices for comics printing. It's from 2017 so a little outdated, but the basics and theory hold up, and the whole comic is $8!
https://store.ironcircus.com/products/lets-print-a-comic
https://store.ironcircus.com/products/lets-print-a-comic
Comments
Updates I'd make: alt programs like Vellum + Affinity Suite weren't super viable in 2017, so I'd talk a bit about 'em. POD is better, and digital printing has added many more fancy options. But the basics are the same.